Powder: -20°C for 3 years | In solvent: -80°C for 1 year
PDE4-IN-10 (compound 7a) is a potent inhibitor of PDE4, with an IC 50 of 7.01 μM for PDE4B. PDE4-IN-10 exhibits selectivity, microsomal stability, inhibition of TNF-α and no major toxicities in vitro [1].
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
25 mg | 6-8 weeks | $ 2,140.00 | |
50 mg | 6-8 weeks | $ 2,785.00 | |
100 mg | 6-8 weeks | $ 3,520.00 |
Description | PDE4-IN-10 (compound 7a) is a potent inhibitor of PDE4, with an IC 50 of 7.01 μM for PDE4B. PDE4-IN-10 exhibits selectivity, microsomal stability, inhibition of TNF-α and no major toxicities in vitro [1]. |
In vitro | PDE4-IN-10 (compound 7a) exhibits 64.56% inhibition at 10 μM against PDE4B, 54% inhibition at 30 μM but 17% inhibition at 10 μM against PDE4D which indicates its selectivity (~3.8 fold) towards PDE4B over PDE4D [1]. |
Molecular Weight | 243.3 |
Formula | C18H13N |
CAS No. | 2413564-66-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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PDE4-IN-10 2413564-66-4 inhibitor inhibit