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DTP3 TFA (1809784-29-9 free base)

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Catalog No. TP1430
Alias DTP3 TFA

DTP3 TFA (1809784-29-9 free base) (DTP3 TFA) is a potent and selective GADD45β/MKK7 (growth arrest and DNA-damage-inducible β/mitogen-activated protein kinase kinase 7) inhibitor.

DTP3 TFA (1809784-29-9 free base)

DTP3 TFA (1809784-29-9 free base)

Copy Product Info
😃Good
Catalog No. TP1430Alias DTP3 TFA
DTP3 TFA (1809784-29-9 free base) (DTP3 TFA) is a potent and selective GADD45β/MKK7 (growth arrest and DNA-damage-inducible β/mitogen-activated protein kinase kinase 7) inhibitor.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$34-In Stock
5 mg$78-In Stock
10 mg$137-In Stock
25 mg$221-In Stock
50 mg$329-In Stock
100 mg$473-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Batch Information

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Purity:>99.99%
Appearance:Solid
Color:White
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Product Introduction

Bioactivity
Description
DTP3 TFA (1809784-29-9 free base) (DTP3 TFA) is a potent and selective GADD45β/MKK7 (growth arrest and DNA-damage-inducible β/mitogen-activated protein kinase kinase 7) inhibitor.
SynonymsDTP3 TFA
Chemical Properties
Molecular Weight639.62
FormulaC28H36F3N7O7
SmilesOc2ccc(C[C@@H](NC(C)=O)C(=O)N[C@H](CCCNC(=N)N)C(=O)N[C@H](Cc1ccccc1)C(N)=O)cc2.FC(F)(F)C(=O)O
Relative Density.no data available
SequenceAc-D-Tyr-D-Arg-D-Phe-NH2
Sequence ShortYRF
Storage & Solubility Information
Storagekeep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 50 mg/mL (78.17 mM), Sonication is recommended.
H2O: 100 mg/mL (156.34 mM), Sonication is recommended.
Solution Preparation Table
DMSO/H2O
1mg5mg10mg50mg
1 mM1.5634 mL7.8171 mL15.6343 mL78.1714 mL
5 mM0.3127 mL1.5634 mL3.1269 mL15.6343 mL
10 mM0.1563 mL0.7817 mL1.5634 mL7.8171 mL
20 mM0.0782 mL0.3909 mL0.7817 mL3.9086 mL
50 mM0.0313 mL0.1563 mL0.3127 mL1.5634 mL
H2O
1mg5mg10mg50mg
100 mM0.0156 mL0.0782 mL0.1563 mL0.7817 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

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