Powder: -20°C for 3 years | In solvent: -80°C for 1 year
PROTAC CYP1B1 Degrader-1 (Compound 6C), an α-naphthoflavone chimera derivative, effectively targets and degrades cytochrome P450 (CYP) 1B1 to overcome agent resistance, displaying half-maximal inhibitory concentrations (IC50s) of 95.1 nM for CYP1B1 and 9838.6 nM for CYP1A2. This compound is suitable for investigating prostate cancer characterized by overexpression of CYP1B1 [1].
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Description | PROTAC CYP1B1 Degrader-1 (Compound 6C), an α-naphthoflavone chimera derivative, effectively targets and degrades cytochrome P450 (CYP) 1B1 to overcome agent resistance, displaying half-maximal inhibitory concentrations (IC50s) of 95.1 nM for CYP1B1 and 9838.6 nM for CYP1A2. This compound is suitable for investigating prostate cancer characterized by overexpression of CYP1B1 [1]. |
Molecular Weight | 785.8 |
Formula | C43H39N5O10 |
CAS No. | 2411389-67-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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PROTAC CYP1B1 degrader-1 2411389-67-6 inhibitor inhibit