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Ferroptosis-IN-6

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Catalog No. T86417Cas No. 1517780-59-4

Ferroptosis-IN-6 is a potent ferroptosis inhibitor that protects cells from ferroptosis-induced cell death and inhibits STY-BODIPY oxidation. It is used in studies of ischemia-reperfusion injury.

Ferroptosis-IN-6

Ferroptosis-IN-6

😃Good
Purity: 99.84%
Catalog No. T86417Cas No. 1517780-59-4
Ferroptosis-IN-6 is a potent ferroptosis inhibitor that protects cells from ferroptosis-induced cell death and inhibits STY-BODIPY oxidation. It is used in studies of ischemia-reperfusion injury.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$52In StockIn Stock
5 mg$123In StockIn Stock
10 mg$197In StockIn Stock
25 mg$396In StockIn Stock
50 mg$637In StockIn Stock
100 mg$987-In Stock
1 mL x 10 mM (in DMSO)$135In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:99.84%
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Product Introduction

Bioactivity
Description
Ferroptosis-IN-6 is a potent ferroptosis inhibitor that protects cells from ferroptosis-induced cell death and inhibits STY-BODIPY oxidation. It is used in studies of ischemia-reperfusion injury.
Targets&IC50
Ferroptosis:25.5 nM (EC50)
In vitro
Ferroptosis-IN-6 (compound 13) is a potent Ferroptosis inhibitor with an EC50 of 25.5 nM. [1]
In vivo
Ferroptosis-IN-6 can effectively protect mice from renal ischemia-reperfusion injury. [1]
Chemical Properties
Molecular Weight227.3
FormulaC15H17NO
Cas No.1517780-59-4
SmilesOC=1C(=CC=CC1C)NCC2=CC=C(C=C2)C
ColorBlue
AppearanceSolid
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 15 mg/mL (65.99 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM4.3995 mL21.9974 mL43.9947 mL219.9736 mL
5 mM0.8799 mL4.3995 mL8.7989 mL43.9947 mL
10 mM0.4399 mL2.1997 mL4.3995 mL21.9974 mL
20 mM0.2200 mL1.0999 mL2.1997 mL10.9987 mL
50 mM0.0880 mL0.4399 mL0.8799 mL4.3995 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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