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Anti-ATP1B4 Antibody (2T513)
😃Good
Catalog No. TMAY-02440
Alias ATPase, Na+/K+ transporting, β 4 polypeptide, ATPase, Na+/K+ transporting, beta 4 polypeptide
Anti-ATP1B4 Antibody (2T513) is a Rabbit antibody targeting ATP1B4. Anti-ATP1B4 Antibody (2T513) can be used in ELISA.
Anti-ATP1B4 Antibody (2T513)
Anti-ATP1B4 Antibody (2T513)
😃Good
Catalog No. TMAY-02440Alias ATPase, Na+/K+ transporting, β 4 polypeptide, ATPase, Na+/K+ transporting, beta 4 polypeptide
Anti-ATP1B4 Antibody (2T513) is a Rabbit antibody targeting ATP1B4. Anti-ATP1B4 Antibody (2T513) can be used in ELISA.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $270 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Antibody Type: Rabbit Monoclonal Application: ELISA Reactivity: Human |
| Alias | ATPase, Na+/K+ transporting, β 4 polypeptide, ATPase, Na+/K+ transporting, beta 4 polypeptide |
| Ig Type | Rabbit IgG |
| Clone | 2T513 |
| Reactivity | Human |
| Application | ELISA |
| Recommended Dose | ELISA: 1:25000-1:50000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human ATP1B4 (mature form, NP_036201.1; Tyr 132-Thr 357). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | ATP1B4 is a member of the X(+)/potassium ATPases subunit beta family. It is highly expressed in skeletal muscle and at a lower level in heart. ATP1B4 gene can be found in all vertebrate genomes sequenced to date. However, this gene has undergone a change in function in placental mammals compared to other species. Specifically, in fish, avian, and amphibian species, this gene encodes plasma membrane-bound beta-subunits of Na, K-ATPase. In placental mammals, the encoded protein interacts with the nuclear transcriptional coregulator SKIP and may be involved in the regulation of TGF-beta signaling. ATP1B4 may act as a transcriptional coregulator during muscle development through its interaction with SNW1. Na+, K+-ATPase is an important regulator of intracellular electrolyte levels in most mammalian cells. It is a Mg2+-dependent transport pump responsible for maintaining the low intracellular Na+:K+ ratio that is essential for cell homeostasis and physiological function. It catalyzes the active uptake of K+ and extrusion of Na+ at the expense of hydrolyzing ATP with a stoichiometry of 3 Na+ for 2 K+. ATP1B4 has lost its ancestral function as a Na,K-ATPase beta-subunit. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Human ATP1B4 protein |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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