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Anti-GLS1 Polyclonal Antibody
(Synonyms: L-glutamine amidohydrolase, KIAA0838, K-glutaminase, KGA, Glutaminase kidney isoform, mitochondrial, GLSK, GLS, GDPAG, GAM, GAC, EIEE71, EC:3.5.1.2, DEE71, CASGID, AAD20) Copy Product Info
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Synonyms: L-glutamine amidohydrolase, KIAA0838, K-glutaminase, KGA, Glutaminase kidney isoform, mitochondrial, GLSK, GLS, GDPAG, GAM, GAC, EIEE71, EC:3.5.1.2, DEE71, CASGID, AAD20
Catalog No. TMAB-00779 Copy Product Info
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Anti-GLS1 Polyclonal Antibody is a Rabbit antibody targeting GLS1. Anti-GLS1 Polyclonal Antibody can be used in ELISA, WB.
Anti-GLS1 Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $222 | 7-10 days | 7-10 days | |
| 100 μL | $373 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
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| Description | Anti-GLS1 Polyclonal Antibody is a Rabbit antibody targeting GLS1. Anti-GLS1 Polyclonal Antibody can be used in ELISA, WB. |
| Synonyms | L-glutamine amidohydrolase, KIAA0838, K-glutaminase, KGA, Glutaminase kidney isoform, mitochondrial, GLSK, GLS, GDPAG, GAM, GAC, EIEE71, EC:3.5.1.2, DEE71, CASGID, AAD20 |
| Ig Type | IgG |
| Reactivity | Human,Mouse,Rat |
| Application | |
| Recommended Dose | ELISA=1:5000-10000; WB=1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Isoform 1: Cytoplasm, cytosol. Isoform 3: Mitochondrion. |
| Tissue Specificity | Isoform 1 and isoform 3 are detected in brain cortex. Isoform 3 is highly expressed in astrocytoma, ganglioglioma and ependymoma. Isoform 1 is highly expressed in brain and kidney, but not detected in liver. Isoform 3 is highly expressed in heart and panc |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | This gene encodes the K-type mitochondrial glutaminase. The encoded protein is an phosphate-activated amidohydrolase that catalyzes the hydrolysis of glutamine to glutamate and ammonia. This protein is primarily expressed in the brain and kidney plays an essential role in generating energy for metabolism, synthesizing the brain neurotransmitter glutamate and maintaining acid-base balance in the kidney. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2012]. |
| Immunogen | KLH conjugated synthetic peptide: human GLS1 |
| Antigen Species | Human |
| Gene Name | GLS |
| Gene ID | |
| Protein Name | Glutaminase kidney isoform, mitochondrial |
| Uniprot ID | |
| Biology Area | Amino acid metabolism,Glutamate,Amino Acids |
| Function | Catalyzes the first reaction in the primary pathway for the renal catabolism of glutamine. Plays a role in maintaining acid-base homeostasis. Regulates the levels of the neurotransmitter glutamate in the brain. Isoform 2 lacks catalytic activity. |
| Molecular Weight | Theoretical: 72 kDa. Actual: 60-65 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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