keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Ssm Spooky Toxin, derived from Scolopendra mutilans, exhibits potent lethality affecting both hematological and respiratory systems primarily through the inhibition of KCNQ (voltage-gated potassium channel family 7) channels. It demonstrates IC50 values of 2.8 μM for Kv7.4, 5.26 μM for Kv1.3, and 0.1-0.3 M for the Shal channel, respectively. Additionally, this toxin impedes cytokine production by selectively targeting the KV1.3 channel in T cells and is crucial for the centipede's circulatory system functions [1] [2] [3].
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Description | Ssm Spooky Toxin, derived from Scolopendra mutilans, exhibits potent lethality affecting both hematological and respiratory systems primarily through the inhibition of KCNQ (voltage-gated potassium channel family 7) channels. It demonstrates IC50 values of 2.8 μM for Kv7.4, 5.26 μM for Kv1.3, and 0.1-0.3 M for the Shal channel, respectively. Additionally, this toxin impedes cytokine production by selectively targeting the KV1.3 channel in T cells and is crucial for the centipede's circulatory system functions [1] [2] [3]. |
Targets&IC50 | Kv1.3:5.26±0.56 μM, KV7.4:2.8±0.25 μM |
Synonyms | SsTx Toxin |
Molecular Weight | 6017.84 |
Formula | C270H413N69O79S4 |
keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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Ssm spooky toxin Membrane transporter/Ion channel Potassium Channel SsTx Toxin inhibitor inhibit