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CMP-Sialic acid sodium salt

Name: CMP-Sialic acid sodium salt
Brand: TargetMol
SKU: T10851
Price: 44 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T10851Cas No. 1007117-62-5

Alias CMP-Neu5Ac sodium salt

CMP-Sialic acid sodium salt (CMP-Neu5Ac sodium salt) is a variant inhibitor of UDP-GlcNAc 2-epimerase, the activated form of sialic acid, which is widely found in animals and is involved in the metabolism of organisms.

CMP-Sialic acid sodium salt

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Purity: 99.23%

Catalog No. T10851Alias CMP-Neu5Ac sodium saltCas No. 1007117-62-5

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$44	In Stock	In Stock
5 mg	$130	In Stock	In Stock
10 mg	$226	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:99.23%

Appearance:Solid

Color:White

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description	CMP-Sialic acid sodium salt (CMP-Neu5Ac sodium salt) is a variant inhibitor of UDP-GlcNAc 2-epimerase, the activated form of sialic acid, which is widely found in animals and is involved in the metabolism of organisms.
In vitro	CMP-Sialic acid (CMP-Neu5Ac) is the activated form of Neu5Ac, a common activating sugar donor for all silyltransferases that transfers individual silyl acids to acceptors or growing oligosaccharide chains [2].
Synonyms	CMP-Neu5Ac sodium salt

Chemical Properties

Molecular Weight	636.43
Formula	C₂₀H₃₀N₄NaO₁₆P
Cas No.	1007117-62-5
Smiles	O[C@H]([C@@H]1O)[C@H](N2C(N=C(C=C2)N)=O)O[C@@H]1COP(O[C@@]3(O[C@@]([C@@H]([C@H](C3)O)NC(C)=O)([H])[C@H](O)[C@H](O)CO)C([O-])=O)(O)=O.[Na+]
Relative Density.	no data available

Storage & Solubility Information

Storage

store at low temperature,keep away from moisture,keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

H2O: 100 mg/mL (157.13 mM), Sonication is recommended.

Solution Preparation Table

H2O

	1mg	5mg	10mg	50mg
1 mM	1.5713 mL	7.8563 mL	15.7126 mL	78.5632 mL
5 mM	0.3143 mL	1.5713 mL	3.1425 mL	15.7126 mL
10 mM	0.1571 mL	0.7856 mL	1.5713 mL	7.8563 mL
20 mM	0.0786 mL	0.3928 mL	0.7856 mL	3.9282 mL
50 mM	0.0314 mL	0.1571 mL	0.3143 mL	1.5713 mL
100 mM	0.0157 mL	0.0786 mL	0.1571 mL	0.7856 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc