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Anti-Prostaglandin D2 Synthase Antibody (9Y228) is a Mouse antibody targeting Prostaglandin D2 Synthase. Anti-Prostaglandin D2 Synthase Antibody (9Y228) can be used in ELISA.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 μL | $198 | 7-10 days |
Description | Anti-Prostaglandin D2 Synthase Antibody (9Y228) is a Mouse antibody targeting Prostaglandin D2 Synthase. Anti-Prostaglandin D2 Synthase Antibody (9Y228) can be used in ELISA. |
Alias | prostaglandin D2 synthase 21kDa (brain) |
Ig Type | Monoclonal Mouse IgG1 |
Clone | 9Y228 |
Reactivity | Human |
Application | ELISA |
Recommended Dose | ELISA: 1:1000-1:2000 |
Antibody Type | Monoclonal |
Host Species | Mouse |
Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human PTGDS / L-PGDS (rh PTGDS / L-PGDS; TMPY-03120; P41222; Met1-Gln190). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
Purification | Protein A |
Appearance | Liquid |
Formulation | 0.2 μm filtered solution in PBS |
Research Background | PTGDS, also known as L-PGDS, belongs to the calycin superfamily, lipocalin family. Lipocalins share limited regions of sequence homology and a common tertiary structure architecture. They transport small hydrophobic molecules such as steroids, bilins, retinoids, and lipids. PTGDS is a glutathione-independent prostaglandin D synthase that catalyzes the conversion of PGH2 to PGD2. It is involved in smooth muscle contraction/relaxation and a variety of central nervous system functions. PTGDS may have an anti-apoptotic role in oligodendrocytes. It binds small non-substrate lipophilic molecules, including biliverdin, bilirubin, retinal, retinoic acid and thyroid hormone, and may act as a scavenger for harmful hydrophopic molecules and as a secretory retinoid and thyroid hormone transporter. It is likely to play important roles in both maturation and maintenance of the central nervous system and male reproductive system. |
Conjucates | Unconjugated |
Immunogen | Recombinant Human PTGDS / L-PGDS Protein (TMPY-03120) |
Antigen Species | Human |
Biology Area | Neurotransmitter Associated Enzymes |
Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
Transport | Shipping with blue ice. |
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