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Synonyms: Tumor amplified and overexpressed sequence 2, Transmembrane protein 16A(eight membrane spanning domains), Transmembrane protein 16A, TMEM16A, TMEM 16A, TAOS2, TAOS 2, ORAOV2, ORAOV 2, Oral cancer overexpressed protein 2, Oral cancer overexpressed 2, Membrane protein, FLJ10261, DOG1, DOG 1, Discovered on gastrointestinal stromal tumors protein 1, Anoctamin1, Anoctamin 1 calcium activated chloride channel, Anoctamin 1, ANO1
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $221 | 7-10 days | 7-10 days | |
| 100 μL | $373 | 7-10 days | 7-10 days | |
| 200 μL | $529 | 7-10 days | 7-10 days |
| Description | Anti-Anoctamin-1/ANO1 Polyclonal Antibody is a Rabbit antibody targeting Anoctamin-1/ANO1. Anti-Anoctamin-1/ANO1 Polyclonal Antibody can be used in IF,IHC-Fr,IHC-P,WB. |
| Synonyms | Tumor amplified and overexpressed sequence 2, Transmembrane protein 16A(eight membrane spanning domains), Transmembrane protein 16A, TMEM16A, TMEM 16A, TAOS2, TAOS 2, ORAOV2, ORAOV 2, Oral cancer overexpressed protein 2, Oral cancer overexpressed 2, Membrane protein, FLJ10261, DOG1, DOG 1, Discovered on gastrointestinal stromal tumors protein 1, Anoctamin1, Anoctamin 1 calcium activated chloride channel, Anoctamin 1, ANO1 |
| Ig Type | IgG |
| Reactivity | Human,Mouse,Rat (predicted:Dog,Pig,Cow,Horse) |
| Application | |
| Recommended Dose | WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cell membrane; Multi-pass membrane protein. Cytoplasm. |
| Tissue Specificity | Broadly expressed with higher levels in liver and skeletal muscle. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | TMEM16A (Transmembrane protein 16A) is an eight-transmembrane protein homologous to C12orf3, C11orf25 and FLJ34272 gene products and is amplified in various cancers. It acts as a calcium-activated chloride channel and is required for normal tracheal development. |
| Immunogen | KLH conjugated synthetic peptide: human DOG-1/TMEM16A |
| Antigen Species | Human |
| Gene Name | ANO1 |
| Gene ID | |
| Protein Name | Anoctamin-1 |
| Uniprot ID | |
| Biology Area | Tumor Associated |
| Function | Acts as a calcium-activated chloride channel. Required for normal tracheal development (By similarity). |
| Molecular Weight | Theoretical: 114 kDa. Actual: 120 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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