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IYPTNGYTR

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Catalog No. T38906Cas No. 1431957-72-0

IYPTNGYTR, a deamidation-sensitive peptide, is a deamidation derivative of Trastuzumab. This compound, IYPTNGYTR, can be utilized for monitoring Trastuzumab metabolism in vivo.

IYPTNGYTR

IYPTNGYTR

😃Good
Catalog No. T38906Cas No. 1431957-72-0
IYPTNGYTR, a deamidation-sensitive peptide, is a deamidation derivative of Trastuzumab. This compound, IYPTNGYTR, can be utilized for monitoring Trastuzumab metabolism in vivo.
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25 mg$1,520InquiryInquiry
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
IYPTNGYTR, a deamidation-sensitive peptide, is a deamidation derivative of Trastuzumab. This compound, IYPTNGYTR, can be utilized for monitoring Trastuzumab metabolism in vivo.
In vitro
IYPTNGYTR undergoes deamidation at pH 7.5 and above, with the deamidation rate increasing as pH rises [1].
Chemical Properties
Molecular Weight1084.199
FormulaC49H73N13O15
Cas No.1431957-72-0
SmilesCC[C@H](C)[C@H](N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(O)=O
Sequence ShortIYPTNGYTR
Storage & Solubility Information
Storagekeep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Stock solution preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (stock solution concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
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IYPTNGYTR
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