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LIGHT/TNFSF14 Trimer Protein, Human, Recombinant (His & Flag)

Catalog No. TMPK-00130
Synonyms: TNFSF14,  TR2, CD258, LTg, LIGHT, HVEM-L

LIGHT, also known as tumor necrosis factor superfamily member 14 (TNFSF14), is a secreted protein of the TNF superfamily. It is recognized by herpesvirus entry mediator (HVEM), as well as decoy receptor 3.This protein has been shown to stimulate the proliferation of T cells, and trigger apoptosis of various tumor cells.

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LIGHT/TNFSF14 Trimer Protein, Human, Recombinant (His & Flag)
Pack Size Availability Price/USD Quantity
100 μg 5 days $ 418.00
500 μg 5 days $ 1,670.00
1 mg 5 days $ 2,800.00
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Biological Description
Technical Params
Product Properties
References and Literature
Description LIGHT, also known as tumor necrosis factor superfamily member 14 (TNFSF14), is a secreted protein of the TNF superfamily. It is recognized by herpesvirus entry mediator (HVEM), as well as decoy receptor 3.This protein has been shown to stimulate the proliferation of T cells, and trigger apoptosis of various tumor cells.
Species Human
Expression System HEK293 Cells
Tag N-His-Flag
Accession Number O43557-1
Synonyms TNFSF14,  TR2, CD258, LTg, LIGHT, HVEM-L
Construction Ser89-Val240 Trimer
Protein Purity > 90% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
Molecular Weight 52.4 kDa (predicted). Due to glycosylation, the protein migrates to 53-140 kDa under Non reducing (N) condition based on Tris-Bis PAGE result.
Endotoxin < 1 EU/μg by the LAL method.
Formulation Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization.
Reconstitution Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Stability & Storage

It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

Shipping

In general, Lyophilized powders are shipping with blue ice.

Research Background LIGHT, also known as tumor necrosis factor superfamily member 14 (TNFSF14), is a secreted protein of the TNF superfamily. It is recognized by herpesvirus entry mediator (HVEM), as well as decoy receptor 3.This protein has been shown to stimulate the proliferation of T cells, and trigger apoptosis of various tumor cells.

References and Literature

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Keywords

LIGHT/TNFSF14 Trimer Protein, Human, Recombinant (His & Flag) TNFSF-14 TNFSF14  TR2 CD 258 CD258 LTg LIGHT HVEM-L CD-258 TR2 TR 2 TNFSF 14 TR-2 recombinant recombinant-proteins proteins protein

 

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