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PD 81723
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Catalog No. T23130Cas No. 132861-87-1
Alias PD-81723, PD81723
PD 81723 is an adenosine receptor binding enhancer that potentiates the inhibitory effects of exogenous adenosine in a dose-dependent manner in hippocampal brain sections, PD 81723 is commonly applied in neuroscience research to investigate adenosine receptor modulation, synaptic transmission, neuromodulation, and neuroprotective signaling pathways.
PD 81723
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Purity: 99.97%
Catalog No. T23130Alias PD-81723, PD81723Cas No. 132861-87-1
PD 81723 is an adenosine receptor binding enhancer that potentiates the inhibitory effects of exogenous adenosine in a dose-dependent manner in hippocampal brain sections, PD 81723 is commonly applied in neuroscience research to investigate adenosine receptor modulation, synaptic transmission, neuromodulation, and neuroprotective signaling pathways.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | $39 | - | In Stock | |
| 5 mg | $89 | - | In Stock | |
| 10 mg | $143 | - | In Stock | |
| 25 mg | $328 | - | In Stock | |
| 50 mg | $533 | - | In Stock | |
| 100 mg | $855 | - | In Stock |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:99.97%
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| Description | PD 81723 is an adenosine receptor binding enhancer that potentiates the inhibitory effects of exogenous adenosine in a dose-dependent manner in hippocampal brain sections, PD 81723 is commonly applied in neuroscience research to investigate adenosine receptor modulation, synaptic transmission, neuromodulation, and neuroprotective signaling pathways. |
| In vitro | In rat hippocampal slices, PD 81723 (10-50 μM) acted as a selective allosteric enhancer of the Adenosine A1 receptor. It potentiated the inhibitory effect of adenosine and 2-chloroadenosine on synaptic transmission and enhanced the depression of population spike amplitude in the CA1 region [1]. |
| Synonyms | PD-81723, PD81723 |
| Molecular Weight | 299.31 |
| Formula | C14H12F3NOS |
| Cas No. | 132861-87-1 |
| Smiles | O=C(C1=CC=CC(=C1)C(F)(F)F)C2=C(SC(=C2C)C)N |
| Relative Density. | 1.31g/cm3 |
| Color | Yellow |
| Appearance | Solid |
| Storage | keep away from moisture | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 80 mg/mL (267.28 mM), Sonication is recommended. Ethanol: <29.93 mg/mL, Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。Stock solution preparation method: 2 mg of drug dissolved in 50 μL DMSO (stock solution concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(stock solution concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarifyThe above example illustrates how to use "In Vivo Formulation Calculator" and does not represent a recommended formulation for any specific compound. Please select an appropriate dissolution method based on your experimental animals and route of administration.
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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