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Anti-Exendin-4 Polyclonal Antibody
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Catalog No. TMAB-00645
Alias Exendin4, Exendin 4, EXE4_HELSU
Anti-Exendin-4 Polyclonal Antibody is a Rabbit antibody targeting Exendin-4. Anti-Exendin-4 Polyclonal Antibody can be used in ELISA,IF,IHC-Fr,IHC-P,WB.
Anti-Exendin-4 Polyclonal Antibody
Anti-Exendin-4 Polyclonal Antibody
😃Good
Catalog No. TMAB-00645Alias Exendin4, Exendin 4, EXE4_HELSU
Anti-Exendin-4 Polyclonal Antibody is a Rabbit antibody targeting Exendin-4. Anti-Exendin-4 Polyclonal Antibody can be used in ELISA,IF,IHC-Fr,IHC-P,WB.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $221 | 7-10 days | |
| 100 μL | $374 | 7-10 days | |
| 200 μL | $528 | 7-10 days |
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-Exendin-4 Polyclonal Antibody is a Rabbit antibody targeting Exendin-4. Anti-Exendin-4 Polyclonal Antibody can be used in ELISA,IF,IHC-Fr,IHC-P,WB. |
| Synonyms | Exendin4, Exendin 4, EXE4_HELSU |
| Ig Type | IgG |
| Reactivity | (predicted:Gila monster lizard) |
| Application | |
| Recommended Dose | WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500; ELISA: 1:5000-10000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Secreted. |
| Tissue Specificity | Expressed by the venom gland. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | Exendin 4 is a 39 amino acid peptide found in venom from the Gila monster Helicoderma suspectum. It is a member of the glucagon secretin family of peptide hormones and neuropeptides. Exendin 4 is a potent agonist of the GLP1 receptor and hence a potent stimulator of insulin secretion. |
| Immunogen | KLH conjugated synthetic peptide: Gila monster lizard Exendin 4 |
| Protein Name | Exendin-4 |
| Biology Area | Diabetes,Metabolic disorders,Obesity,Hormones |
| Function | Venom protein that mimics the incretin hormone glucagon-like peptide 1 (GLP-1). It stimulates insulin synthesis and secretion, protects against beta-cell apoptosis in response to different insults, and promotes beta-cell proliferation. It also promotes satiety, reduces food intake, reduces fat deposition, reduces body weight and inhibits gastric emptying. Interacts with GLP-1 receptor (GLP1R). Induces hypotension that is mediated by relaxation of cardiac smooth muscle. |
| Molecular Weight | Theoretical: 4.3 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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