IL-7 Protein, Human, Recombinant

Name: IL-7 Protein, Human, Recombinant
Brand: TargetMol
SKU: TMPY-03383
Price: 78 USD
Availability: InStock
Rating: 5 (10 reviews)

(Synonyms: Interleukin-7, interleukin 7, IL-7) Copy Product Info

Synonyms: Interleukin-7, interleukin 7, IL-7

Catalog No. TMPY-03383 Copy Product Info

IL-7 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 17.5 kDa and the accession number is P13232-1.

Pack Size	Price	USA Stock	Global Stock
5 µg	$78	-	In Stock
10 µg	$126	In Stock	In Stock
20 µg	$192	7-10 days	7-10 days
50 µg	$329	7-10 days	7-10 days
100 µg	$498	7-10 days	7-10 days
200 µg	$851	7-10 days	7-10 days
500 µg	$1,730	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Purity:SDS-PAGE: 97.4%; SEC-HPLC: 97.9%

Appearance:Lyophilized powder

Color:White

Resource Download

COA User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Measured in a cell proliferation assay using anti-CD3 antibody activated human peripheral blood mononuclear cell (PBMC). The ED50 for this effect is typically 0.5-8 ng/ml.
Description	IL-7 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 17.5 kDa and the accession number is P13232-1.
Species	Human
Expression System	E. coli
Tag	Tag Free
Accession Number	P13232-1
Construction	A DNA sequence encoding the mature form of human IL7 (NP_000871.1)(Asp26-His177) was expressed with a N-terminal Met. Predicted N terminal: Met
Protein Purity	≥ 95 % as determined by SDS-PAGE. ≥ 95 % as determined by SEC-HPLC. ,
Endotoxin	< 0.01 EU/μg of the protein.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
Reconstitution	Reconstituted with sterile deionized water to 0.25 mg/mL. Reconstitution conditions may vary depending on the lot.
Synonyms	Interleukin-7, interleukin 7, IL-7
Research Background	IL7, also known as interleukin 7, is a hematopoietic growth factor that belongs to the IL-7/IL-9 family. It is secreted by stromal cells in the bone marrow and thymus. IL7 stimulates the proliferation of lymphoid progenitors. It is important for proliferation during certain stages of B-cell maturation. IL7 and the hepatocyte growth factor (HGF) form a heterodimer that functions as a pre-pro-B cell growth-stimulating factor. It is found to be a cofactor for V(D)J rearrangement of the T cell receptor beta (TCRß) during early T cell development. IL7 can be produced locally by intestinal epithelial and epithelial goblet cells and may serve as a regulatory factor for intestinal mucosal lymphocytes.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy

Chemical Properties

Molecular Weight

17.5 kDa (predicted); 16.44 kDa (reducing conditions)

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.