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Anti-Carboxypeptidase A Antibody (5M381)

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Catalog No. TMAY-00913
Alias CPA, carboxypeptidase A1 (pancreatic)

Anti-Carboxypeptidase A Antibody (5M381) is a Mouse antibody targeting Carboxypeptidase A. Anti-Carboxypeptidase A Antibody (5M381) can be used in IHC-P.

Anti-Carboxypeptidase A Antibody (5M381)

Anti-Carboxypeptidase A Antibody (5M381)

😃Good
Catalog No. TMAY-00913Alias CPA, carboxypeptidase A1 (pancreatic)
Anti-Carboxypeptidase A Antibody (5M381) is a Mouse antibody targeting Carboxypeptidase A. Anti-Carboxypeptidase A Antibody (5M381) can be used in IHC-P.
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100 μL$199 7-10 days
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Product Introduction

Bioactivity
Description
Anti-Carboxypeptidase A Antibody (5M381) is a Mouse antibody targeting Carboxypeptidase A. Anti-Carboxypeptidase A Antibody (5M381) can be used in IHC-P.
AliasCPA, carboxypeptidase A1 (pancreatic)
Ig Type
Monoclonal Mouse IgG1
Clone
5M381
Reactivity
Human
Verified Activity
Immunochemical staining of human CPA1 in human pancreas with mouse monoclonal antibody (1:60, formalin-fixed paraffin embedded sections).
Application
IHC-P
Recommended Dose
IHC-P: 1:50-1:200
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionThis antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human Carboxypeptidase A1 / CPA1 (rh Carboxypeptidase A1 / CPA1; TMPY-01729; NP_001859.1; Met1-Tyr419). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundCarboxypeptidase A1 (CPA1)is secreted as a pancreatic procarboxypeptidase, and cleaves the C-terminal amide or ester bond of peptides that have a free C-terminal carboxyl group, with the preference of residues with aromatic or branched aliphatic side chains. CPA1 comprises a signal peptide, a pro region and a mature chain, and can be activated after cleavage of the pro peptide. In contrast to procarboxypeptidase B which was always secreted by the pancreas as a monomer, procarboxypeptidase A occurs as a monomer and/or associated to one or two functionally different proteins, such as zymogen E, and is involved in zymogen inhibition. Three different forms of human pancreatic procarboxypeptidase A have been isolated.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Human Carboxypeptidase A1 / CPA1 Protein (TMPY-01729)
Antigen Species
Human
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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