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Anti-Carboxypeptidase A Antibody (5M381) is a Mouse antibody targeting Carboxypeptidase A. Anti-Carboxypeptidase A Antibody (5M381) can be used in IHC-P.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 μL | $199 | 7-10 days |
Description | Anti-Carboxypeptidase A Antibody (5M381) is a Mouse antibody targeting Carboxypeptidase A. Anti-Carboxypeptidase A Antibody (5M381) can be used in IHC-P. |
Alias | CPA, carboxypeptidase A1 (pancreatic) |
Ig Type | Monoclonal Mouse IgG1 |
Clone | 5M381 |
Reactivity | Human |
Verified Activity | Immunochemical staining of human CPA1 in human pancreas with mouse monoclonal antibody (1:60, formalin-fixed paraffin embedded sections). |
Application | IHC-P |
Recommended Dose | IHC-P: 1:50-1:200 |
Antibody Type | Monoclonal |
Host Species | Mouse |
Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human Carboxypeptidase A1 / CPA1 (rh Carboxypeptidase A1 / CPA1; TMPY-01729; NP_001859.1; Met1-Tyr419). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
Purification | Protein A |
Appearance | Liquid |
Formulation | 0.2 μm filtered solution in PBS |
Research Background | Carboxypeptidase A1 (CPA1)is secreted as a pancreatic procarboxypeptidase, and cleaves the C-terminal amide or ester bond of peptides that have a free C-terminal carboxyl group, with the preference of residues with aromatic or branched aliphatic side chains. CPA1 comprises a signal peptide, a pro region and a mature chain, and can be activated after cleavage of the pro peptide. In contrast to procarboxypeptidase B which was always secreted by the pancreas as a monomer, procarboxypeptidase A occurs as a monomer and/or associated to one or two functionally different proteins, such as zymogen E, and is involved in zymogen inhibition. Three different forms of human pancreatic procarboxypeptidase A have been isolated. |
Conjucates | Unconjugated |
Immunogen | Recombinant Human Carboxypeptidase A1 / CPA1 Protein (TMPY-01729) |
Antigen Species | Human |
Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
Transport | Shipping with blue ice. |
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