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1-Deoxysphingosine (m18:1(4E))

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Catalog No. T38214Cas No. 193222-34-3
Alias 1-Deoxysphingosine (m18:1(4E))

1-Deoxysphingosine (m18:1(4E)) is an atypical sphingolipid that contains a double bond at the 4E native position and is formed when serine palmitoyltransferase condenses palmitoyl-CoA with alanine instead of serine during sphingolipid synthesis.1,2 Plasma levels of 1-deoxysphingosine (m18:1(4E)) are increased in patients with chronic idiopathic axonal neuropathy (CIAP) and diabetic distal symmetrical polyneuropathy (DSPN).3

1-Deoxysphingosine (m18:1(4E))
Other Forms of 1-Deoxysphingosine (m18:1(4E)):
1-Deoxysphingosine (m18:1(14Z))T852562190487-94-4
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1-Deoxysphingosine (m18:1(4E))

😃Good
Catalog No. T38214Alias 1-Deoxysphingosine (m18:1(4E))Cas No. 193222-34-3
1-Deoxysphingosine (m18:1(4E)) is an atypical sphingolipid that contains a double bond at the 4E native position and is formed when serine palmitoyltransferase condenses palmitoyl-CoA with alanine instead of serine during sphingolipid synthesis.1,2 Plasma levels of 1-deoxysphingosine (m18:1(4E)) are increased in patients with chronic idiopathic axonal neuropathy (CIAP) and diabetic distal symmetrical polyneuropathy (DSPN).3
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
500 μg$38335 days35 days
1 mg$71735 days35 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
1-Deoxysphingosine (m18:1(4E)) is an atypical sphingolipid that contains a double bond at the 4E native position and is formed when serine palmitoyltransferase condenses palmitoyl-CoA with alanine instead of serine during sphingolipid synthesis.1,2 Plasma levels of 1-deoxysphingosine (m18:1(4E)) are increased in patients with chronic idiopathic axonal neuropathy (CIAP) and diabetic distal symmetrical polyneuropathy (DSPN).3
Synonyms1-Deoxysphingosine (m18:1(4E))
Chemical Properties
Molecular Weight283.5
FormulaC18H37NO
Cas No.193222-34-3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 2 mg/mL (7.05 mM), Sonication is recommended.
Ethanol: Miscible
DMF: 10 mg/mL (35.27 mM), Sonication is recommended.
Solution Preparation Table
DMSO/DMF
1mg5mg10mg50mg
1 mM3.5273 mL17.6367 mL35.2734 mL176.3668 mL
5 mM0.7055 mL3.5273 mL7.0547 mL35.2734 mL
DMF
1mg5mg10mg50mg
10 mM0.3527 mL1.7637 mL3.5273 mL17.6367 mL
20 mM0.1764 mL0.8818 mL1.7637 mL8.8183 mL

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Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
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Keywords

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