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Anti-HLA-DR Antibody-PE (4D493)

🥰Excellent
Catalog No. TMAY-03604P

Anti-HLA-DR Antibody-PE (4D493) is a PE-conjugated Mouse antibody targeting HLA-DR. Anti-HLA-DR Antibody-PE (4D493) can be used in FCM.

Anti-HLA-DR Antibody-PE (4D493)

Anti-HLA-DR Antibody-PE (4D493)

🥰Excellent
Catalog No. TMAY-03604P
Anti-HLA-DR Antibody-PE (4D493) is a PE-conjugated Mouse antibody targeting HLA-DR. Anti-HLA-DR Antibody-PE (4D493) can be used in FCM.
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Product Introduction

Bioactivity
Description
Anti-HLA-DR Antibody-PE (4D493) is a PE-conjugated Mouse antibody targeting HLA-DR. Anti-HLA-DR Antibody-PE (4D493) can be used in FCM.
Ig Type
Monoclonal Mouse IgG1
Clone
4D493
Reactivity
Human
Verified Activity
Flow cytometric analysis of Human HLA-DR expression on human whole blood lymphocytes. Cells were stained with PE-conjugated anti-Human HLA-DR. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of viable lymphocytes.
Application
FCM
Recommended Dose
0.5 μl/Test, 0.1 mg/ml
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionThe monoclonal antibody was purified by affinity chromatography. Then it was conjugated with PE under optimum conditions, and the unreacted PE was removed.
AppearanceLiquid
FormulationPBS solution containing 0.5% BSA and 0.09% sodium azide
Research BackgroundHLA-DR is a major histocompatibility complex (MHC) class II antigen presentation molecule, critical for the activation of lymphocytes and the orchestration of adaptive immune responses. HLA-DR is normally expressed on antigen-presenting cells including monocytes, macrophages, dendritic cells and B cells, but expression can be induced on epithelial cells and tumour cells in response to inflammatory conditions. MHC class II antigen presentation molecules are responsible for presentation of exogenous antigens to CD4+helper T cells. HLA-DR expression in tumours has been positively associated with enhanced lymphocytic infiltration. HLA-DR has been used as a surrogate marker of immune competence in various clinical studies, and its loss in circulation has been linked with susceptibility to post-surgical infection and sepsis.
Related Conjugates and Formulations
Conjucates
PE
Others Formats
FITC
Antibody Types Available
2
Antigen Details
Immunogen
0
Antigen Species
Human
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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