Shopping Cart
- Remove All
- Your shopping cart is currently empty
Anti-HLA-DR Antibody-PE (4D493) is a PE-conjugated Mouse antibody targeting HLA-DR. Anti-HLA-DR Antibody-PE (4D493) can be used in FCM.
Description | Anti-HLA-DR Antibody-PE (4D493) is a PE-conjugated Mouse antibody targeting HLA-DR. Anti-HLA-DR Antibody-PE (4D493) can be used in FCM. |
Ig Type | Monoclonal Mouse IgG1 |
Clone | 4D493 |
Reactivity | Human |
Verified Activity | Flow cytometric analysis of Human HLA-DR expression on human whole blood lymphocytes. Cells were stained with PE-conjugated anti-Human HLA-DR. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of viable lymphocytes. |
Application | FCM |
Recommended Dose | 0.5 μl/Test, 0.1 mg/ml |
Antibody Type | Monoclonal |
Host Species | Mouse |
Construction | The monoclonal antibody was purified by affinity chromatography. Then it was conjugated with PE under optimum conditions, and the unreacted PE was removed. |
Appearance | Liquid |
Formulation | PBS solution containing 0.5% BSA and 0.09% sodium azide |
Research Background | HLA-DR is a major histocompatibility complex (MHC) class II antigen presentation molecule, critical for the activation of lymphocytes and the orchestration of adaptive immune responses. HLA-DR is normally expressed on antigen-presenting cells including monocytes, macrophages, dendritic cells and B cells, but expression can be induced on epithelial cells and tumour cells in response to inflammatory conditions. MHC class II antigen presentation molecules are responsible for presentation of exogenous antigens to CD4+helper T cells. HLA-DR expression in tumours has been positively associated with enhanced lymphocytic infiltration. HLA-DR has been used as a surrogate marker of immune competence in various clinical studies, and its loss in circulation has been linked with susceptibility to post-surgical infection and sepsis. |
Conjucates | PE |
Others Formats | FITC |
Antibody Types Available | 2 |
Immunogen | 0 |
Antigen Species | Human |
Stability & Storage | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal. |
Transport | Shipping with blue ice. |
Copyright © 2015-2025 TargetMol Chemicals Inc. All Rights Reserved.