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2-(2-bromophenyl)-5-chloro-4H-3,1-benzoxazin-4-one

🥰Excellent
Catalog No. T8563Cas No. 1234707-32-4

2-(2-bromophenyl)-5-chloro-4H-3,1-benzoxazin-4-one is an human neutrophil elastase inhibitor.

2-(2-bromophenyl)-5-chloro-4H-3,1-benzoxazin-4-one

2-(2-bromophenyl)-5-chloro-4H-3,1-benzoxazin-4-one

🥰Excellent
Purity: 97.36%
Catalog No. T8563Cas No. 1234707-32-4
2-(2-bromophenyl)-5-chloro-4H-3,1-benzoxazin-4-one is an human neutrophil elastase inhibitor.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$47In StockIn Stock
5 mg$107In StockIn Stock
10 mg$163In StockIn Stock
25 mg$269In StockIn Stock
50 mg$378In StockIn Stock
100 mg$511In StockIn Stock
200 mg$697In StockIn Stock
1 mL x 10 mM (in DMSO)$112In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:97.36%
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COA HNMR LCMS

Product Introduction

Bioactivity
Description
2-(2-bromophenyl)-5-chloro-4H-3,1-benzoxazin-4-one is an human neutrophil elastase inhibitor.
Chemical Properties
Molecular Weight336.57
FormulaC14H7BrClNO2
Cas No.1234707-32-4
SmilesBrC1=C(C2=NC=3C(C(=O)O2)=C(Cl)C=CC3)C=CC=C1
Relative Density.1.65 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 3.37 mg/mL (10.01 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.9712 mL14.8558 mL29.7115 mL148.5575 mL
5 mM0.5942 mL2.9712 mL5.9423 mL29.7115 mL
10 mM0.2971 mL1.4856 mL2.9712 mL14.8558 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
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Keywords

SerineProteaseSerine ProteaseNeutrophil elastase (human)2(2bromophenyl)5chloro4H3,1benzoxazin4one2 (2 bromophenyl) 5 chloro 4H 3,1 benzoxazin 4 one
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