Shopping Cart

Your shopping cart is currently empty

Pamabrom

Name: Pamabrom
Brand: TargetMol
SKU: T1230
Price: 46 USD
Availability: InStock
Rating: 5 (10 reviews)

Copy Product Info

😃Good

Catalog No. T1230Cas No. 606-04-2

Pamabrom is a diuretic, used for the relief of temporary water weight gain, bloating, swelling and full feeling associated with the premenstrual and menstrual periods.

Pamabrom

Copy Product Info

😃Good

Purity: 99.9%

Catalog No. T1230Cas No. 606-04-2

Pamabrom is a diuretic, used for the relief of temporary water weight gain, bloating, swelling and full feeling associated with the premenstrual and menstrual periods.

Pack Size	Price	USA Warehouse	Global Warehouse
25 mg	$46	In Stock	In Stock
50 mg	$59	In Stock	In Stock
100 mg	$90	In Stock	In Stock
500 mg	$148	-	In Stock

Add to Cart

Add to Quotation

In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Questions

Batch Information

Select Batch

Purity:99.9%

Appearance:Solid

Color:White

Resource Download

COA HPLC HNMR

Product Introduction

Pamabrom AI Summary

Pamabrom shows no induction of drug-induced liver injury in human liver, as assessed by measuring the severity class index. It has antiviral activity, demonstrated by its ability to inhibit SARS-CoV-2 induced cytotoxicity of Caco-2 cells, with an inhibition of -4.18% at a concentration of 10 µM after 48 hours. Additionally, Pamabrom inhibits the SARS-CoV-2 3CL-Pro protease with an inhibition percentage of 15.8% at a 20 µM concentration, suggesting it might interfere with the virus's protease activity. However, it exhibited 0% inhibition under conditions tested in VERO-6 cells at a 10 µM concentration with 48 hours exposure to 0.01 MOI SARS-CoV-2 virus, as assessed by high content imaging..

Note: Summary generated by AI. Data source: ChEMBL

Bioactivity

Description

Pamabrom is a diuretic, used for the relief of temporary water weight gain, bloating, swelling and full feeling associated with the premenstrual and menstrual periods.

Chemical Properties

Molecular Weight	348.2
Formula	C₁₁H₁₈BrN₅O₃
Cas No.	606-04-2
Smiles	CC(C)(N)CO.Cn1c2nc(Br)[nH]c2c(=O)n(C)c1=O
Relative Density.	no data available

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 150 mg/mL (430.79 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 4 mg/mL (11.49 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.8719 mL	14.3596 mL	28.7191 mL	143.5956 mL
5 mM	0.5744 mL	2.8719 mL	5.7438 mL	28.7191 mL
10 mM	0.2872 mL	1.4360 mL	2.8719 mL	14.3596 mL
20 mM	0.1436 mL	0.7180 mL	1.4360 mL	7.1798 mL
50 mM	0.0574 mL	0.2872 mL	0.5744 mL	2.8719 mL
100 mM	0.0287 mL	0.1436 mL	0.2872 mL	1.4360 mL

Calculator

Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc