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Anti-TNFR1/CD120a/TNFRSF1A Antibody (1K754)

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Catalog No. TMAC-04069

Anti-TNFR1/CD120a/TNFRSF1A Antibody (1K754) is a Mouse antibody targeting TNFR1/CD120a/TNFRSF1A. Anti-TNFR1/CD120a/TNFRSF1A Antibody (1K754) can be used in WB,IP,IF,IHC-P.

Anti-TNFR1/CD120a/TNFRSF1A Antibody (1K754)

Anti-TNFR1/CD120a/TNFRSF1A Antibody (1K754)

😃Good
Catalog No. TMAC-04069
Anti-TNFR1/CD120a/TNFRSF1A Antibody (1K754) is a Mouse antibody targeting TNFR1/CD120a/TNFRSF1A. Anti-TNFR1/CD120a/TNFRSF1A Antibody (1K754) can be used in WB,IP,IF,IHC-P.
Pack SizePriceAvailabilityQuantity
50 μL$2967-10 days
100 μL$4287-10 days
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Product Introduction

Bioactivity
Description
Anti-TNFR1/CD120a/TNFRSF1A Antibody (1K754) is a Mouse antibody targeting TNFR1/CD120a/TNFRSF1A. Anti-TNFR1/CD120a/TNFRSF1A Antibody (1K754) can be used in WB,IP,IF,IHC-P.
Reactivity
Human,Mouse,Rat
Application
Recommended Dose
WB: 1:100-1000; IHC-P: 1:50-500; IP: 1-2 μg per 100-500 μg of total protein(1 ml of cell lysate)
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionHybridoma Monoclonal Antibody
PurificationImmunogen affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundTumor necrosis factor (TNF) is a pleiotropic cytokine whose function is mediated through two distinct cell surface receptors. These receptors, designated TNF-R1 and TNF-R2 are expressed on most cell types. The majority of TNF functions are primarily mediated through TNF-R1, while signaling through TNF-R2 occurs less extensively and is confined to cells of the immune system. Both of these proteins belong to the growing TNF and nerve growth factor (NGF) receptor superfamily, which includes FAS, CD30, CD27 and CD40. The members of this superfamily are type I membrane proteins that share sequence homology confined to the extracellular region. TNF-R1 shares a motif coined the “death domain” with FAS and three structurally unrelated signaling proteins, TRADD, FADD and RIP. This “death domain” is required for transduction of the apoptotic signal.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Amino acids 30-301 mapping within the extracellular domain of TNF-R1 of human origin
Antigen Species
human
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 55 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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