HLA-G Free Heavy Chain Protein, Human, Recombinant (His & Avi)

Catalog No. TMPK-00836

HLA-G is a molecule that was first known to confer protection to the fetus from destruction by the immune system of its mother, thus critically contributing to fetal-maternal tolerance. The first functional finding constituted the basis for HLA-G research and can be summarized as such: HLA-G, membrane-bound or soluble, strongly binds its inhibitory receptors on immune cells (NK, T, B, monocytes/dendritic cells), inhibits the functions of these effectors, and so induces immune inhibition.

HLA-G Free Heavy Chain Protein, Human, Recombinant (His & Avi)

Catalog No. TMPK-00836

Pack Size	Price	USA Warehouse	Global Warehouse
5 μg	$44	7-10 days	7-10 days
10 μg	$68	7-10 days	7-10 days
20 μg	$108	7-10 days	7-10 days
50 μg	$198	7-10 days	7-10 days
100 μg	$347	7-10 days	7-10 days
200 μg	$628	7-10 days	7-10 days
500 μg	$1,400	7-10 days	7-10 days

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In Stock Estimated shipping dateUSA Warehouse [1-2 days] Global Warehouse [5-7 days]

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User Guide of Recombinant Proteins

Product Information

Biological Activity	Immobilized Human HLA-G Free Heavy Chain, His Tag at 2μg/ml (100μl/Well) on the. Dose response curve for Anti-HLA-G Antibody, hFc Tag with the EC50 of 25.9ng/ml determined by ELISA.
Description	HLA-G is a molecule that was first known to confer protection to the fetus from destruction by the immune system of its mother, thus critically contributing to fetal-maternal tolerance. The first functional finding constituted the basis for HLA-G research and can be summarized as such: HLA-G, membrane-bound or soluble, strongly binds its inhibitory receptors on immune cells (NK, T, B, monocytes/dendritic cells), inhibits the functions of these effectors, and so induces immune inhibition.
Species	Human
Expression System	E. coli
Tag	C-His-Avi
Accession Number	P17693-1
Synonyms	sHLA-G,MHC-G,MHC class Ib antigen,MHC Class I Antigen G,HLA-G,HLAG,HLA G antigen,HLA G,b2 microglobulin
Construction	Gly25-Thr305(C66S)
Protein Purity	> 95% as determined by Tris-Bis PAGE
Molecular Weight	35.5 kDa (predicted). The protein migrates to 36-40 kDa based on Tris-Bis PAGE result.
Endotoxin	< 1 EU/μg by the LAL method.
Formulation	Supplied as 0.22 μm filtered solution in 20 mM Tris, 500 mM NaCl, 20% Glycerol (pH 8.0).
Stability & Storage	It is recommended to store the product under sterile conditions at -70°C or lower. Samples are stable for up to 12 months at -80°C. Please avoid multiple freeze-thaw cycles and store products in aliquots.
Shipping	Shipping with blue ice.
Research Background	HLA-G is a molecule that was first known to confer protection to the fetus from destruction by the immune system of its mother, thus critically contributing to fetal-maternal tolerance. The first functional finding constituted the basis for HLA-G research and can be summarized as such: HLA-G, membrane-bound or soluble, strongly binds its inhibitory receptors on immune cells (NK, T, B, monocytes/dendritic cells), inhibits the functions of these effectors, and so induces immune inhibition.

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