HLA-G Free Heavy Chain Protein, Human, Recombinant (His & Avi)

Name: HLA-G Free Heavy Chain Protein, Human, Recombinant (His & Avi)
Brand: TargetMol
SKU: TMPK-00836
Rating: 4.5 (1 reviews)

(Synonyms: sHLA-G, MHC-G, MHC class Ib antigen, MHC Class I Antigen G, HLA-G, HLAG, HLA G antigen, HLA G, b2 microglobulin) Copy Product Info

Synonyms: sHLA-G, MHC-G, MHC class Ib antigen, MHC Class I Antigen G, HLA-G, HLAG, HLA G antigen, HLA G, b2 microglobulin

Catalog No. TMPK-00836 Copy Product Info

HLA-G is a molecule that was first known to confer protection to the fetus from destruction by the immune system of its mother, thus critically contributing to fetal-maternal tolerance. The first functional finding constituted the basis for HLA-G research and can be summarized as such: HLA-G, membrane-bound or soluble, strongly binds its inhibitory receptors on immune cells (NK, T, B, monocytes/dendritic cells), inhibits the functions of these effectors, and so induces immune inhibition.

HLA-G Free Heavy Chain Protein, Human, Recombinant (His & Avi)

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Pack Size	Price	USA Stock	Global Stock
5 μg	$44	7-10 days	7-10 days
10 μg	$68	7-10 days	7-10 days
20 μg	$108	7-10 days	7-10 days
50 μg	$198	7-10 days	7-10 days
100 μg	$347	7-10 days	7-10 days
200 μg	$628	7-10 days	7-10 days
500 μg	$1,400	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

Questions

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User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Immobilized Human HLA-G Free Heavy Chain, His Tag at 2μg/ml (100μl/Well) on the. Dose response curve for Anti-HLA-G Antibody, hFc Tag with the EC50 of 25.9ng/ml determined by ELISA.
Description	HLA-G is a molecule that was first known to confer protection to the fetus from destruction by the immune system of its mother, thus critically contributing to fetal-maternal tolerance. The first functional finding constituted the basis for HLA-G research and can be summarized as such: HLA-G, membrane-bound or soluble, strongly binds its inhibitory receptors on immune cells (NK, T, B, monocytes/dendritic cells), inhibits the functions of these effectors, and so induces immune inhibition.
Species	Human
Expression System	E. coli
Tag	C-His-Avi
Accession Number	P17693-1
Construction	Gly25-Thr305(C66S)
Protein Purity	> 95% as determined by Tris-Bis PAGE
Endotoxin	< 1.0 EU/μg of the protein as determined by the LAL method.
Formulation	Supplied as 0.22 μm filtered solution in 20 mM Tris, 500 mM NaCl, 20% Glycerol (pH 8.0).
Stability & Storage	It is recommended to store the product under sterile conditions at -70°C or lower. Samples are stable for up to 12 months at -80°C. Please avoid multiple freeze-thaw cycles and store products in aliquots.
Shipping	Proteins are shipped with blue ice.
Synonyms	sHLA-G, MHC-G, MHC class Ib antigen, MHC Class I Antigen G, HLA-G, HLAG, HLA G antigen, HLA G, b2 microglobulin
Research Background

Chemical Properties

Molecular Weight

35.5 kDa (predicted). The protein migrates to 36-40 kDa based on Tris-Bis PAGE result.

Storage & Solubility Information

Storage

Store at low temperature Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months

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Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Related Tags: HLA-G Free Heavy Chain Protein, Human, Recombinant (His & Avi) chemical structure | HLA-G Free Heavy Chain Protein, Human, Recombinant (His & Avi) molecular weight