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HLA-G Free Heavy Chain Protein, Human, Recombinant (His & Avi)
(Synonyms: sHLA-G, MHC-G, MHC class Ib antigen, MHC Class I Antigen G, HLA-G, HLAG, HLA G antigen, HLA G, b2 microglobulin) Copy Product InfoSynonyms: sHLA-G, MHC-G, MHC class Ib antigen, MHC Class I Antigen G, HLA-G, HLAG, HLA G antigen, HLA G, b2 microglobulin
Catalog No. TMPK-00836 Copy Product Info
HLA-G is a molecule that was first known to confer protection to the fetus from destruction by the immune system of its mother, thus critically contributing to fetal-maternal tolerance. The first functional finding constituted the basis for HLA-G research and can be summarized as such: HLA-G, membrane-bound or soluble, strongly binds its inhibitory receptors on immune cells (NK, T, B, monocytes/dendritic cells), inhibits the functions of these effectors, and so induces immune inhibition.
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| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 10 µg | $68 | 7-10 days | 7-10 days | |
| 20 µg | $108 | 7-10 days | 7-10 days | |
| 50 µg | $198 | 7-10 days | 7-10 days | |
| 100 µg | $347 | 7-10 days | 7-10 days | |
| 200 µg | $628 | 7-10 days | 7-10 days | |
| 500 µg | $1,400 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Bioactivity | Immobilized Human HLA-G Free Heavy Chain, His Tag at 2μg/ml (100μl/Well) on the. Dose response curve for Anti-HLA-G Antibody, hFc Tag with the EC50 of 25.9ng/ml determined by ELISA. |
| Description | HLA-G is a molecule that was first known to confer protection to the fetus from destruction by the immune system of its mother, thus critically contributing to fetal-maternal tolerance. The first functional finding constituted the basis for HLA-G research and can be summarized as such: HLA-G, membrane-bound or soluble, strongly binds its inhibitory receptors on immune cells (NK, T, B, monocytes/dendritic cells), inhibits the functions of these effectors, and so induces immune inhibition. |
| Species | Human |
| Expression System | E. coli |
| Tag | C-His-Avi |
| Accession Number | P17693-1 |
| Construction | Gly25-Thr305(C66S) |
| Protein Purity | > 95% as determined by Tris-Bis PAGE |
| Endotoxin | < 1.0 EU/μg of the protein as determined by the LAL method. |
| Formulation | Supplied as 0.22 μm filtered solution in 20 mM Tris, 500 mM NaCl, 20% Glycerol (pH 8.0). |
| Synonyms | sHLA-G, MHC-G, MHC class Ib antigen, MHC Class I Antigen G, HLA-G, HLAG, HLA G antigen, HLA G, b2 microglobulin |
| Research Background | HLA-G is a molecule that was first known to confer protection to the fetus from destruction by the immune system of its mother, thus critically contributing to fetal-maternal tolerance. The first functional finding constituted the basis for HLA-G research and can be summarized as such: HLA-G, membrane-bound or soluble, strongly binds its inhibitory receptors on immune cells (NK, T, B, monocytes/dendritic cells), inhibits the functions of these effectors, and so induces immune inhibition. |
| Molecular Weight | 35.5 kDa (predicted). The protein migrates to 36-40 kDa based on Tris-Bis PAGE result. |
| Shipping | Proteins are shipped with blue ice. |
| Storage | It is recommended to store the product under sterile conditions at -70°C or lower. Samples are stable for up to 12 months at -80°C. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
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Related Tags: HLA-G Free Heavy Chain Protein, Human, Recombinant (His & Avi) chemical structure | HLA-G Free Heavy Chain Protein, Human, Recombinant (His & Avi) molecular weight
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