Contact UsQuotation
Shopping Cart
Remove All
  • TargetMol
    Your shopping cart is currently empty
Proceed to checkoutContinue shopping
TOPBioactivityChemical infoStorage&SolubilityCalculator

N-Fmoc-N'-(azido-PEG4)-L-Lysine-PFP ester

😃Good
Catalog No. T18414

N-Fmoc-N'-(azido-PEG4)-L-Lysine-PFP ester is an alkyl/ether-based linker for PROTACs, facilitating the connection of two essential ligands critical for forming PROTAC molecules. This linker enables selective protein degradation by utilizing the ubiquitin-proteasome system within cells.

N-Fmoc-N'-(azido-PEG4)-L-Lysine-PFP ester

N-Fmoc-N'-(azido-PEG4)-L-Lysine-PFP ester

😃Good
Catalog No. T18414
N-Fmoc-N'-(azido-PEG4)-L-Lysine-PFP ester is an alkyl/ether-based linker for PROTACs, facilitating the connection of two essential ligands critical for forming PROTAC molecules. This linker enables selective protein degradation by utilizing the ubiquitin-proteasome system within cells.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
100 mgInquiryInquiryInquiry
500 mgInquiryInquiryInquiry
Add to Quotation
In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Questions
TargetMol
View More

Resource Download

Product Introduction

Bioactivity
Description
N-Fmoc-N'-(azido-PEG4)-L-Lysine-PFP ester is an alkyl/ether-based linker for PROTACs, facilitating the connection of two essential ligands critical for forming PROTAC molecules. This linker enables selective protein degradation by utilizing the ubiquitin-proteasome system within cells.
In vitro
PROTACs consist of two ligands linked together: one targets an E3 ubiquitin ligase, while the other binds to a specific protein. They leverage the intracellular ubiquitin-proteasome system to selectively degrade target proteins [1].
Chemical Properties
Molecular Weight807.76
FormulaC38H42F5N5O9
SmilesO=C(NCCCC[C@H](NC(OCC1C(C=CC=C2)=C2C3=C1C=CC=C3)=O)C(OC4=C(F)C(F)=C(F)C(F)=C4F)=O)CCOCCOCCOCCOCCN=[N+]=[N-]
Relative Density.no data available
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Calculator

  • Molarity Calculator
  • Dilution Calculator
  • Reconstitution Calculator
  • Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

NFmocN'(azidoPEG4)LLysinePFP esterN-Fmoc-N'-(azido-PEG4)-L-Lysine-PFP esterN-Fmoc-N'-(azido-PEG-4)-L-Lysine-PFP esterN Fmoc N' (azido PEG4) L Lysine PFP esterAlkyl/ether
Related Tags: buy N-Fmoc-N'-(azido-PEG4)-L-Lysine-PFP ester | purchase N-Fmoc-N'-(azido-PEG4)-L-Lysine-PFP ester | N-Fmoc-N'-(azido-PEG4)-L-Lysine-PFP ester cost | order N-Fmoc-N'-(azido-PEG4)-L-Lysine-PFP ester | N-Fmoc-N'-(azido-PEG4)-L-Lysine-PFP ester chemical structure | N-Fmoc-N'-(azido-PEG4)-L-Lysine-PFP ester in vitro | N-Fmoc-N'-(azido-PEG4)-L-Lysine-PFP ester formula | N-Fmoc-N'-(azido-PEG4)-L-Lysine-PFP ester molecular weight
TargetMol | Logo

Copyright © 2015-2025 TargetMol Chemicals Inc. All Rights Reserved.