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UBE2B Protein, Human, Recombinant (His)

Catalog No. TMPJ-00033
Synonyms: Ubiquitin-Conjugating Enzyme E2 B, hHR6B, Ubiquitin-Conjugating Enzyme E2-17 kDa, RAD6 Homolog B, HR6B, RAD6B, Ubiquitin Carrier Protein B, UBE2B, Ubiquitin-Protein Ligase B

Ubiquitin-Conjugating Enzyme E2 B (UBE2B) is a member of the ubiquitin-conjugating enzyme family. UBE2B accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. It is shown that UBE2B interacts with RAD18, UBR2, and WAC. UBE2B is required for post-replicative DNA damage repair. Additional, UBE2B plays a role in sepsis-induced muscle protein proteolysis and cancer-induced cachexia.

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UBE2B Protein, Human, Recombinant (His)
Pack Size Availability Price/USD Quantity
10 μg 5 days $ 129.00
50 μg 5 days $ 390.00
500 μg 5 days $ 1,900.00
1 mg 5 days $ 2,730.00
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Biological Description
Technical Params
Product Properties
Description Ubiquitin-Conjugating Enzyme E2 B (UBE2B) is a member of the ubiquitin-conjugating enzyme family. UBE2B accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. It is shown that UBE2B interacts with RAD18, UBR2, and WAC. UBE2B is required for post-replicative DNA damage repair. Additional, UBE2B plays a role in sepsis-induced muscle protein proteolysis and cancer-induced cachexia.
Species Human
Expression System Human Cells
Tag C-6His
Accession Number P63146
Synonyms Ubiquitin-Conjugating Enzyme E2 B, hHR6B, Ubiquitin-Conjugating Enzyme E2-17 kDa, RAD6 Homolog B, HR6B, RAD6B, Ubiquitin Carrier Protein B, UBE2B, Ubiquitin-Protein Ligase B
Amino Acid Met1-Ser152
Construction Recombinant Human Ubiquitin-Conjugating Enzyme E2 B is produced by our Mammalian expression system and the target gene encoding Met1-Ser152 is expressed with a 6His tag at the C-terminus.
Protein Purity Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
Molecular Weight 17 KDa, reducing conditions
Endotoxin Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation Supplied as a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
Stability & Storage

Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.

Shipping

The product is shipped on dry ice/polar packs. Upon receipt, store it immediately at the temperature listed below.

Research Background Ubiquitin-Conjugating Enzyme E2 B (UBE2B) is a member of the ubiquitin-conjugating enzyme family. UBE2B accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. It is shown that UBE2B interacts with RAD18, UBR2, and WAC. UBE2B is required for post-replicative DNA damage repair. Additional, UBE2B plays a role in sepsis-induced muscle protein proteolysis and cancer-induced cachexia.

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Keywords

UBE2B Protein, Human, Recombinant (His) Ubiquitin-Conjugating Enzyme E2 B hHR6B Ubiquitin-Conjugating Enzyme E2-17 kDa RAD6 Homolog B HR6B RAD6B Ubiquitin Carrier Protein B UBE2B Ubiquitin-Protein Ligase B recombinant recombinant-proteins proteins protein

 

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