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Anti-PTGER2 Polyclonal Antibody

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Catalog No. TMAB-01592
Alias PTGER 2, Prostanoid EP2 receptor, Prostaglandin E2 receptor EP2 subtype, PGE2 receptor EP2 subtype, PGE receptor EP2 subtype

Anti-PTGER2 Polyclonal Antibody is a Rabbit antibody targeting PTGER2. Anti-PTGER2 Polyclonal Antibody can be used in WB.

Anti-PTGER2 Polyclonal Antibody

Anti-PTGER2 Polyclonal Antibody

😃Good
Catalog No. TMAB-01592Alias PTGER 2, Prostanoid EP2 receptor, Prostaglandin E2 receptor EP2 subtype, PGE2 receptor EP2 subtype, PGE receptor EP2 subtype
Anti-PTGER2 Polyclonal Antibody is a Rabbit antibody targeting PTGER2. Anti-PTGER2 Polyclonal Antibody can be used in WB.
Pack SizePriceAvailabilityQuantity
50 μL$2207-10 days
100 μL$3727-10 days
200 μL$5277-10 days
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Product Introduction

Bioactivity
Description
Anti-PTGER2 Polyclonal Antibody is a Rabbit antibody targeting PTGER2. Anti-PTGER2 Polyclonal Antibody can be used in WB.
AliasPTGER 2, Prostanoid EP2 receptor, Prostaglandin E2 receptor EP2 subtype, PGE2 receptor EP2 subtype, PGE receptor EP2 subtype
Ig Type
IgG
Reactivity
Human,Mouse,Rat,Sheep (predicted:Dog,Pig,Cow,Rabbit)
Verified Activity
Sample:
Lane 1: Mouse Spleen tissue lysates
Lane 2: Mouse Urinary bladder tissue lysates
Lane 3: Mouse Placenta tissue lysates
Lane 4: Rat Urinary bladder tissue lysates
Lane 5: Rat Placenta tissue lysates
Lane 6: Human MCF-7 cell lysates
Lane 7: Human JAR cell lysates
Lane 8: Human HL60 cell lysates
Primary: Anti-PTGER2 (TMAB-01592) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 40 kDa
Observed band size: 48 kDa
Application
WB
Recommended Dose
WB: 1:500-2000
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationCell membrane; Multi-pass membrane protein.
ConstructionHybridoma Polyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Research BackgroundProstaglandins are produced by the metabolism of arachidonic acid. Prostaglandin E2 is one of the five physiologically significant prostanoids known. Its wide spectrum of physiologic and pharmacologic effects in various tissues is mediated through binding to the Prostaglandin E2 receptors (EP1, EP2, EP3 & EP4). These include effects on the immune, endocrine, cardiovascular, renal and reproductive systems as well as smooth muscle. It is also one of the most abundant of the prostanoid family in the brain where it plays an important role in many neural functions, particularly in newborn babies, and as a mediator of inflammation. Prostaglandin E2 signals through a family of G-protein coupled receptors known as EP receptors. There are 4 subtypes of EP receptors, known as EP1, EP2, EP3 and EP4. EP2 receptors are 358 amino acid proteins with a short third intracellular loop. EP2 receptors stimulate adenylyl cyclase by their coupling to Gs and do not undergo Prostaglandin E2 induced internalization. The EP2 receptors is involved with the contration and relaxation of smooth muscle tissue. These receptors are mainly localized in lung and placental tissues and in smooth muscle.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human Prostaglandin E Receptor EP2
Antigen Species
Human
Gene ID
Uniprot ID
Biology Area
Lipid metabolism,Prostaglandins
Chemical Properties
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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