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Gly-Arg-Gly-Asp-Ser acetate(96426-21-0 free base)

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Catalog No. TP1459L

Gly-Arg-Gly-Asp-Ser (GRGDS) acetate is a cell binding protein domain derived from the cell-binding region of fibronectin.

Gly-Arg-Gly-Asp-Ser acetate(96426-21-0 free base)
Other Forms of Gly-Arg-Gly-Asp-Ser acetate(96426-21-0 free base):

Gly-Arg-Gly-Asp-Ser acetate(96426-21-0 free base)

🥰Excellent
Purity: 99.81%
Catalog No. TP1459L
Gly-Arg-Gly-Asp-Ser (GRGDS) acetate is a cell binding protein domain derived from the cell-binding region of fibronectin.
Pack SizePriceAvailabilityQuantity
2 mg$35In Stock
5 mg$61In Stock
10 mg$94In Stock
25 mg$185In Stock
50 mg$280In Stock
100 mg$411In Stock
200 mg$583In Stock
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Batch Information

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Purity:99.81%
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COA MS HPLC

Product Introduction

Bioactivity
Description
Gly-Arg-Gly-Asp-Ser (GRGDS) acetate is a cell binding protein domain derived from the cell-binding region of fibronectin.
Targets&IC50
αvβ5 integrin:6.5 μM, αvβ3 integrin:5 μM
In vitro
Gly-Arg-Gly-Asp-Ser binds to integrin receptors αvβ3, with IC50 of 5 μM[1]. Gly-Arg-Gly-Asp-Ser-immobilized TiO2 nanotubes enhance osteoblast-like cell (MG-63) adhesion, and significantly increased cell spreading and proliferation[2].
Chemical Properties
Molecular Weight550.52
FormulaC19H34N8O11
SmilesC(C[C@@H](C(=O)NCC(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CO)C(=O)O)NC(=O)CN)CN=C(N)N.CC(=O)O
Relative Density.no data available
SequenceH-Gly-Arg-Gly-Asp-Ser-OH.CH3CO2H
Sequence ShortGRGDS
Storage & Solubility Information
Storagekeep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: Insoluble
H2O: 10 mM, Sonication is recommended.
Solution Preparation Table
H2O
1mg5mg10mg50mg
1 mM1.8165 mL9.0823 mL18.1646 mL90.8232 mL
5 mM0.3633 mL1.8165 mL3.6329 mL18.1646 mL
10 mM0.1816 mL0.9082 mL1.8165 mL9.0823 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
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Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
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Keywords

αVβ5 integrinαvβ3 integrinGly-Arg-Gly-Asp-Ser acetate(96426-21-0 free base)GlyArgGlyAspSer acetate(96426210 free base)Gly Arg Gly Asp Ser acetate(96426 21 0 free base)
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