M-CSF/CSF1 Protein, Mouse, Recombinant (CHO)

Name: M-CSF/CSF1 Protein, Mouse, Recombinant (CHO)
Brand: TargetMol
SKU: TMPS-00102
Price: 98 USD
Availability: InStock
Rating: 5 (10 reviews)

(Synonyms: MGI-IM, MGC31930, MCSF, Macrophage Colony Stimulating Factor, Lanimostim, CSF-1, CSF1, colony stimulating factor 1) Copy Product Info

Synonyms: MGI-IM, MGC31930, MCSF, Macrophage Colony Stimulating Factor, Lanimostim, CSF-1, CSF1, colony stimulating factor 1

Catalog No. TMPS-00102 Copy Product Info

M-CSF/CSF1 Protein, Mouse, Recombinant (CHO) is expressed in CHO Cells. The accession number is P07141.

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Pack Size	Price	USA Stock	Global Stock
5 µg	$98	-	In Stock
10 µg	$170	-	In Stock
20 µg	$295	-	In Stock
50 µg	$622	-	In Stock
100 µg	$993	-	In Stock
200 µg	$1,580	7-10 days	7-10 days
500 µg	$2,960	7-10 days	7-10 days
1 mg	$4,750	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Purity:> 95% as analyzed by SDS-PAGE > 95% as analyzed by HPLC

Appearance:Lyophilized powder

Color:White

Resource Download

COA User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	ED 50 < 3.0 ng/ml, measured in a cell proliferation assay using Murine M-NFS-60 cells, corresponding to a specific activity of > 3.3 × 10 5 units/mg.
Description	M-CSF/CSF1 Protein, Mouse, Recombinant (CHO) is expressed in CHO Cells. The accession number is P07141.
Species	Mouse
Expression System	CHO Cells
Tag	Tag Free
Accession Number	P07141
Construction	Lys33-Pro187
Protein Purity	> 95% as determined by SDS-PAGE; > 95% as determined by HPLC
Endotoxin	< 0.2 EU/μg of protein as determined by the LAL method.
Formulation	Lyophilized from a 0.2 μm filtered solution in PBS.
Reconstitution	Reconstitute the lyophilized protein in sterile deionized water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Synonyms	MGI-IM, MGC31930, MCSF, Macrophage Colony Stimulating Factor, Lanimostim, CSF-1, CSF1, colony stimulating factor 1
Research Background	Macrophage-Colony Stimulating Factor (M-CSF), also known as Colony Stimulating Factor-1 (CSF-1), is a hematopoietic growth factor. It can stimulate the survival, proliferation and differentiation of mononuclear phagocytes, in addition to the spreading and motility of macrophages. In mammals, it exits three isoforms, which invariably share an N-terminal 32-aa signal peptide, a 149-residue growth factor domain, a 21-residue transmembrane region and a 37-aa cytoplasmictail. M-CSF is mainly produced by monocytes, macrophages, fibroblasts, and endothelial cells. M-CSF interaction with its receptor, c-fms, has been implicated in the growth, invasion, and metastasis of of several diseases, including breast and endometrial cancers. The biological activity of human M-CSF is maintained within the 149-aa growth factor domain, and it is only active in the disulfide-linked dimeric form, which is bonded at Cys63.

Chemical Properties

Molecular Weight

35~44 kDa (Non-reducing conditions)

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	Upon receiving, this product remains stable for up to 6 months at lower than -70°C. Upon reconstitution, the product should be stable for up to 1 week at 4°C or up to 3 months at -20°C. For long term storage it is recommended that a carrier protein (example 0.1% BSA) be added. Avoid repeated freeze-thaw cycles.