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PIK-inhibitors

Name: PIK-inhibitors
Brand: TargetMol
SKU: T3190
Rating: 4.5 (1 reviews)

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Catalog No. T3190Cas No. 371934-59-7

Alias MDK34597

PIK-inhibitors (MDK34597) is a pan PI3K inhibitors, an analog of PI-103.

PIK-inhibitors

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Purity: 96.98%

Catalog No. T3190Alias MDK34597Cas No. 371934-59-7

PIK-inhibitors (MDK34597) is a pan PI3K inhibitors, an analog of PI-103.

Pack Size	Price	Availability
1 mg	$59	6-8 weeks
5 mg	$136	6-8 weeks
10 mg	$246	6-8 weeks
25 mg	$443	6-8 weeks
50 mg	$573	6-8 weeks

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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Purity:96.98%

Resource Download

COA LCMS HNMR

Product Introduction

Bioactivity

Description	PIK-inhibitors (MDK34597) is a pan PI3K inhibitors, an analog of PI-103.
Synonyms	MDK34597

Chemical Properties

Molecular Weight	347.37
Formula	C₁₉H₁₇N₅O₂
Cas No.	371934-59-7
Smiles	NC=1C=C(C=2N=C3C(=C(N2)N4CCOCC4)OC=5C3=CC=CN5)C=CC1
Relative Density.	1.383 g/cm3 (Predicted)
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 10 mM, Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.8788 mL	14.3939 mL	28.7877 mL	143.9387 mL
5 mM	0.5758 mL	2.8788 mL	5.7575 mL	28.7877 mL
10 mM	0.2879 mL	1.4394 mL	2.8788 mL	14.3939 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Sci Citations

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc