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Hepcidin/HAMP Protein, Mouse, Recombinant (GST)
(Synonyms: PLTR, LEAP-1, LEAP1, HFE2B, Hepc1, Hepc, Hamp1) Copy Product InfoSynonyms: PLTR, LEAP-1, LEAP1, HFE2B, Hepc1, Hepc, Hamp1
Catalog No. TMPK-01170 Copy Product Info
Hepcidin, the main regulator of iron metabolism, is synthesized and released by hepatocytes in response to increased body iron concentration and inflammation. Deregulation of hepcidin expression is a common feature of genetic and acquired iron disorders: in Hereditary Hemochromatosis (HH) and iron-loading anemias low hepcidin causes iron overload, while in Iron Refractory Iron Deficiency Anemia (IRIDA) and anemia of inflammation (AI), high hepcidin levels induce iron-restricted erythropoiesis.
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 5 μg | $56 | 7-10 days | 7-10 days | |
| 10 μg | $88 | 7-10 days | 7-10 days | |
| 20 μg | $143 | 7-10 days | 7-10 days | |
| 50 μg | $278 | 7-10 days | 7-10 days | |
| 100 μg | $465 | 7-10 days | 7-10 days | |
| 200 μg | $839 | 7-10 days | 7-10 days | |
| 500 μg | $1,850 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Bioactivity | Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first. |
| Description | Hepcidin, the main regulator of iron metabolism, is synthesized and released by hepatocytes in response to increased body iron concentration and inflammation. Deregulation of hepcidin expression is a common feature of genetic and acquired iron disorders: in Hereditary Hemochromatosis (HH) and iron-loading anemias low hepcidin causes iron overload, while in Iron Refractory Iron Deficiency Anemia (IRIDA) and anemia of inflammation (AI), high hepcidin levels induce iron-restricted erythropoiesis. |
| Species | Mouse |
| Expression System | E. coli |
| Tag | N-GST |
| Accession Number | Q9EQ21 |
| Construction | Asp59-Thr83 |
| Protein Purity | > 95% as determined by Tris-Bis PAGE |
| Endotoxin | < 1.0 EU/μg of the protein as determined by the LAL method. |
| Formulation | Lyophilized from a solution filtered through a 0.22 μm filter, containing 50 mM Tris-HCl, 150 mM NaCl, 2 mM DTT (pH 7.5). Typically, 8% trehalose is incorporated as a protective agent before lyophilization. |
| Reconstitution | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
| Stability & Storage | It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
| Shipping | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| Synonyms | PLTR, LEAP-1, LEAP1, HFE2B, Hepc1, Hepc, Hamp1 |
| Research Background |
| Molecular Weight | 29.05 kDa (predicted) same as Tris-Bis PAGE result. |
| Storage | Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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Related Tags: Hepcidin/HAMP Protein, Mouse, Recombinant (GST) chemical structure | Hepcidin/HAMP Protein, Mouse, Recombinant (GST) molecular weight
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