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Anti-ANGPT2/Angiopoietin-2 Antibody (7W847) is an antibody targeting ANGPT2/Angiopoietin-2. Anti-ANGPT2/Angiopoietin-2 Antibody (7W847) can be used in ELISA.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $209 | 7-10 days | 7-10 days | |
| 100 μL | $349 | 7-10 days | 7-10 days |
| Description | Anti-ANGPT2/Angiopoietin-2 Antibody (7W847) is an antibody targeting ANGPT2/Angiopoietin-2. Anti-ANGPT2/Angiopoietin-2 Antibody (7W847) can be used in ELISA. |
| Synonyms | Tie2-ligand, ANGPT2, angiopoitin 2, angiopoietin-2B, angiopoietin-2a, Angiopoietin-2, angiopoietin 2, ANG-2, ANG2, AGPT2 |
| Ig Type | Human IgG1 |
| Clone | 7W847 |
| Reactivity | Human |
| Verified Activity | The Binding Activity of ANGPT2 with anti-ANGPT2 antibody Activity: Measured by its binding ability in a functional ELISA. Immobilized Human ANGPT2 at 2 μg/mL can bind Anti-ANGPT2 recombinant antibody, the EC50 is 0.6666-0.8876 ng/mL. |
| Application | |
| Antibody Type | Monoclonal |
| Subcellular Localization | Secreted. |
| Construction | Recombinant Antibody |
| Purification | Affinity-chromatography |
| Appearance | Liquid |
| Formulation | Preservative: 0.03% Proclin 300. Constituents: 50% Glycerol, 0.01M PBS, PH 7.4. |
| Research Background | Binds to TEK/TIE2, competing for the ANGPT1 binding site, and modulating ANGPT1 signaling. Can induce tyrosine phosphorylation of TEK/TIE2 in the absence of ANGPT1. In the absence of angiogenic inducers, such as VEGF, ANGPT2-mediated loosening of cell-matrix contacts may induce endothelial cell apoptosis with consequent vascular regression. In concert with VEGF, it may facilitate endothelial cell migration and proliferation, thus serving as a permissive angiogenic signal. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Human ANGPT2 Protein |
| Antigen Species | Human |
| Gene Name | ANGPT2 |
| Gene ID | |
| Uniprot ID | |
| Biology Area | Immunology |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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