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Anti-ANGPT2/Angiopoietin-2 Antibody (7W847) is an antibody targeting ANGPT2/Angiopoietin-2. Anti-ANGPT2/Angiopoietin-2 Antibody (7W847) can be used in ELISA.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
50 μL | $209 | 7-10 days | |
100 μL | $349 | 7-10 days |
Description | Antibody Type: Recombinant Monoclonal Application: ELISA Reactivity: Human |
Alias | Tie2-ligand, ANGPT2, angiopoitin 2, angiopoietin-2B, angiopoietin-2a, Angiopoietin-2, angiopoietin 2, ANG-2, ANG2, AGPT2 |
Ig Type | Human IgG1 |
Clone | 7W847 |
Reactivity | Human |
Verified Activity | The Binding Activity of ANGPT2 with anti-ANGPT2 antibody Activity: Measured by its binding ability in a functional ELISA. Immobilized Human ANGPT2 at 2 μg/mL can bind Anti-ANGPT2 recombinant antibody, the EC50 is 0.6666-0.8876 ng/mL. |
Application | ELISA |
Antibody Type | Monoclonal |
Subcellular Localization | Secreted. |
Construction | Recombinant Antibody |
Purification | Affinity-chromatography |
Appearance | Liquid |
Formulation | Preservative: 0.03% Proclin 300. Constituents: 50% Glycerol, 0.01M PBS, PH 7.4. |
Research Background | Binds to TEK/TIE2, competing for the ANGPT1 binding site, and modulating ANGPT1 signaling. Can induce tyrosine phosphorylation of TEK/TIE2 in the absence of ANGPT1. In the absence of angiogenic inducers, such as VEGF, ANGPT2-mediated loosening of cell-matrix contacts may induce endothelial cell apoptosis with consequent vascular regression. In concert with VEGF, it may facilitate endothelial cell migration and proliferation, thus serving as a permissive angiogenic signal. |
Conjucates | Unconjugated |
Immunogen | Recombinant Protein: Human ANGPT2 Protein |
Antigen Species | Human |
Gene ID | 285 |
Uniprot ID | |
Biology Area | Immunology |
Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
Transport | Shipping with blue ice. |
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