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TargetMol | Compound Library

Nuclear Receptor Compound Library

Catalog No. L1510

Nuclear receptors are a class of proteins, different from membrane receptors located in the cell membrane, found within cells that are responsible for sensing steroid and thyroid hormones and certain other molecules. Nuclear receptors have the ability to directly bind to DNA and regulate the expression of adjacent genes, hence these receptors are classified as transcription factors, thereby controlling the development, homeostasis, and metabolism of the organism. Over the last 15 years a growing number of nuclear receptors have been identified that coordinate genetic networks regulating lipid metabolism and energy utilization and underlie the pathogenesis of metabolic diseases, such as obesity, type II diabetes, hypertension, and cardiovascular disease. TargetMol collects 631 reported compounds targeting nuclear receptors as Nuclear Receptor Compound Library, which can be used for research in nuclear receptor signaling and related diseases, and high throughput and high content screening for drug discovery.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

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Catalog No. L1510

Nuclear Receptor Compound Library

sizeIn stock

  • 1 mg
  • 30 μL x 10 mM (in DMSO)
  • 50 μL x 10 mM (in DMSO)
  • 100 μL x 10 mM (in DMSO)
  • 250 μL x 10 mM (in DMSO)
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Product Description Product Description

  • A unique collection of 631 nuclear receptor signaling targeted compounds for high throughput and high content screening;
  • Bioactivity and safety confirmed by pre-clinical research and clinical trials;
  • Detailed compound information with structure, target, activity, IC50 value, and biological activity description;
  • Structurally diverse, medicinally active, and cell permeable;
  • NMR and HPLC validated to ensure high purity and quality;

Packaging And Storage Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice
  • This compound library is provided at a concentration of 10 mM in DMSO. A small number of compounds may be provided in different solvents or concentrations due to solubility or stability requirements. Please refer to the specific product information for details.

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Library Customization | TargetMol Library Composition

PPAR
Estrogen/progestogen Receptor
Estrogen Receptor/ERR
Glucocorticoid Receptor
Autophagy
Androgen Receptor
Endogenous Metabolite
Retinoid Receptor
Apoptosis
Progesterone Receptor
FXR
Thyroid hormone receptor(THR)
ROR
AhR
Liver X Receptor
COX
NF-κB
Antibacterial
Cytochromes P450
Aryl Hydrocarbon Receptor
Ferroptosis
TSH Receptor
Reactive Oxygen Species
IL Receptor
Akt
Potassium Channel
Antifungal
GPCR
AMPK
MMP
TNF
Tyrosinase
GPCR19
Mitophagy
Antibiotic
Bcl-2 Family
Adrenergic Receptor
RAR/RXR
Drug Metabolite
Reductase
Annexin A
Influenza Virus
Prostaglandin Receptor
Epigenetic Reader Domain
Nrf2
JNK
Interleukin
NOS
p53
Cannabinoid Receptor
TRP/TRPV Channel
Calcium Channel
Lipoxygenase
SARS-CoV
ROS
p38 MAPK
NO Synthase
ADC Cytotoxin
GSK-3
Caspase
HIV Protease
Parasite
VEGFR
PARP
Sodium Channel
Virus Protease
ERK
Smo
Glutathione Peroxidase
Sirtuin
Histamine Receptor
Aromatase
PDE
transporter
GABA Receptor
Mitochondrial Metabolism
Phosphatase
Wnt/beta-catenin
Antioxidant
ABC Transporter
Nucleoside Antimetabolite/Analog
Proteasome
TAM Receptor
HIF/HIF Prolyl-Hydroxylase
Phospholipase
Phosphorylase
CaMK
GluR
HCV Protease
FLT
Immunology/Inflammation related
DNA
Complement System
MAO
PERK
Dehydrogenase
Histone Methyltransferase
gp120/CD4
AChR
Glucagon Receptor
HBV
HMG-CoA Reductase
PKA
Adenylyl Cyclase
Lipid
Histone Acetyltransferase
Hydroxylase
Melatonin Receptor
P-gp
Glucosidase
LDL
Leukotriene Receptor
mTOR
STAT
c-Kit
S1P Receptor
Gamma-secretase
HSP
PKC
Topoisomerase
DNA Methyltransferase
Cysteine Protease
RAAS
c-Met/HGFR
Glucokinase
DNA/RNA Synthesis
Carbonic Anhydrase
FLAP
Opioid Receptor
STING
Thrombin
MRP
IFNAR
Fatty Acid Synthase
PAK
ATPase
GNRH Receptor
PGC-1α

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