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TargetMol | Compound Library

Nuclear Receptor Compound Library

Catalog No. L1510

Nuclear receptors are a class of proteins, different from membrane receptors located in the cell membrane, found within cells that are responsible for sensing steroid and thyroid hormones and certain other molecules. Nuclear receptors have the ability to directly bind to DNA and regulate the expression of adjacent genes, hence these receptors are classified as transcription factors, thereby controlling the development, homeostasis, and metabolism of the organism. Over the last 15 years a growing number of nuclear receptors have been identified that coordinate genetic networks regulating lipid metabolism and energy utilization and underlie the pathogenesis of metabolic diseases, such as obesity, type II diabetes, hypertension, and cardiovascular disease. TargetMol collects 631 reported compounds targeting nuclear receptors as Nuclear Receptor Compound Library, which can be used for research in nuclear receptor signaling and related diseases, and high throughput and high content screening for drug discovery.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

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Catalog No. L1510

Nuclear Receptor Compound Library

sizeIn stock

  • 1 mg
  • 30 μL x 10 mM (in DMSO)
  • 50 μL x 10 mM (in DMSO)
  • 100 μL x 10 mM (in DMSO)
  • 250 μL x 10 mM (in DMSO)
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Product Description Product Description

  • A unique collection of 631 nuclear receptor signaling targeted compounds for high throughput and high content screening;
  • Bioactivity and safety confirmed by pre-clinical research and clinical trials;
  • Detailed compound information with structure, target, activity, IC50 value, and biological activity description;
  • Structurally diverse, medicinally active, and cell permeable;
  • NMR and HPLC validated to ensure high purity and quality;

Packaging And Storage | TargetMol Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice

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Library Customization | TargetMol Library Customization

Compound Library | TargetMol
Targetmol Compound Libraries
can be highly customized!
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Library Customization | TargetMol Library Composition

PPAR
Estrogen/progestogen Receptor
Estrogen Receptor/ERR
Glucocorticoid Receptor
Autophagy
Androgen Receptor
Endogenous Metabolite
Retinoid Receptor
Apoptosis
Progesterone Receptor
FXR
Thyroid hormone receptor(THR)
ROR
AhR
Liver X Receptor
COX
Antibacterial
NF-κB
Cytochromes P450
Aryl Hydrocarbon Receptor
Ferroptosis
Reactive Oxygen Species
TSH Receptor
GPCR
IL Receptor
RAR/RXR
Akt
AMPK
Potassium Channel
Antifungal
Reductase
Mitophagy
Adrenergic Receptor
Annexin A
Drug Metabolite
MMP
Prostaglandin Receptor
GPCR19
Bcl-2 Family
Influenza Virus
TNF
Tyrosinase
Antibiotic
NOS
p38 MAPK
Parasite
Calcium Channel
TRP/TRPV Channel
ROS
Epigenetic Reader Domain
Lipoxygenase
Interleukin
SARS-CoV
Nrf2
Cannabinoid Receptor
p53
NO Synthase
ADC Cytotoxin
HIV Protease
Antioxidant
Histamine Receptor
JNK
Glutathione Peroxidase
Phosphatase
Virus Protease
GSK-3
Wnt/beta-catenin
PARP
VEGFR
ERK
PDE
ABC Transporter
Mitochondrial Metabolism
Smo
Sirtuin
transporter
Aromatase
GABA Receptor
Sodium Channel
Proteasome
ATPase
Adenylyl Cyclase
Carbonic Anhydrase
Histone Methyltransferase
HCV Protease
Dehydrogenase
c-Met/HGFR
IFNAR
RAAS
PERK
gp120/CD4
Melatonin Receptor
MRP
PKA
GNRH Receptor
HBV
Nucleoside Antimetabolite/Analog
Cysteine Protease
Leukotriene Receptor
Glucokinase
Caspase
PKC
MAO
Immunology/Inflammation related
Topoisomerase
FLAP
LDL
Gamma-secretase
Glucagon Receptor
Phosphorylase
Glucosidase
Opioid Receptor
Fatty Acid Synthase
PAK
Epoxide Hydrolase
GluR
CaMK
DNA
mTOR
Lipid
DNA/RNA Synthesis
P-gp
HSP
STING
Histone Acetyltransferase
STAT
Phospholipase
Hydroxylase
Complement System
AChR
FLT
c-Kit
DNA Methyltransferase
HMG-CoA Reductase
TAM Receptor
Thrombin
HIF/HIF Prolyl-Hydroxylase
S1P Receptor
PGC-1α

Keywords