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Opiranserin

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Catalog No. T16399Cas No. 1441000-45-8

Opiranserin is a development as an injectable agent for the treatment of postoperative pain. Opiranserin is a non-opioid and non-NSAID analgesic candidate and is a dual antagonist of glycine transporter type 2 (GlyT2) and serotonin receptor 2A (5HT2A) (IC50s: 0.86 and 1.3 μM, respectively). Opiranserin displays antagonistic activity on rP2X3 (IC50=0.87 μM).

Opiranserin
Other Forms of Opiranserin:
Opiranserin hydrochlorideT98331440796-75-7
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Opiranserin

😃Good
Catalog No. T16399Cas No. 1441000-45-8
Opiranserin is a development as an injectable agent for the treatment of postoperative pain. Opiranserin is a non-opioid and non-NSAID analgesic candidate and is a dual antagonist of glycine transporter type 2 (GlyT2) and serotonin receptor 2A (5HT2A) (IC50s: 0.86 and 1.3 μM, respectively). Opiranserin displays antagonistic activity on rP2X3 (IC50=0.87 μM).
Pack SizePriceAvailabilityQuantity
25 mg$1,5201-2 weeks
50 mg$1,9801-2 weeks
100 mg$2,5001-2 weeks
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Product Introduction

Bioactivity
Description
Opiranserin is a development as an injectable agent for the treatment of postoperative pain. Opiranserin is a non-opioid and non-NSAID analgesic candidate and is a dual antagonist of glycine transporter type 2 (GlyT2) and serotonin receptor 2A (5HT2A) (IC50s: 0.86 and 1.3 μM, respectively). Opiranserin displays antagonistic activity on rP2X3 (IC50=0.87 μM).
Targets&IC50
GlyT2:0.86 μM, 5-HT2A receptor:1.3 μM, P2X3 (rat):0.87 μM
Chemical Properties
Molecular Weight394.51
FormulaC21H34N2O5
Cas No.1441000-45-8
Relative Density.1.12 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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Keywords

VVZ-149VVZ149VVZ 149Serotonin ReceptorrP2X3postoperativepainP2XRsP2XReceptorP2X ReceptorOpiranserinnon-opioidInhibitorinhibitGlyT2GlyTGlycine transportersanti-inflammatoryanalgesic5-hydroxytryptamine Receptor5HTReceptor5-HT2A Receptor5-HT2A5-HT Receptor5HT Receptor
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