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HO-PEG14-OH is a PEG-based linker for PROTACs, joining two essential ligands crucial for forming PROTAC molecules and enabling selective protein degradation through the ubiquitin-proteasome system within cells.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
10 mg | $32 | Backorder |
Description | HO-PEG14-OH is a PEG-based linker for PROTACs, joining two essential ligands crucial for forming PROTAC molecules and enabling selective protein degradation through the ubiquitin-proteasome system within cells. |
In vitro | PROTACs consist of two distinct ligands linked together: one ligand targets an E3 ubiquitin ligase, while the other binds to the target protein. Utilizing the intracellular ubiquitin-proteasome system, PROTACs facilitate the selective degradation of target proteins[1]. |
Molecular Weight | 634.75 |
Formula | C28H58O15 |
Cas No. | 1189112-05-7 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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