Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Pomalidomide-PEG3-C2-NH2 hydrochloride, also known as Cereblon Ligand-Linker Conjugate 5, is a chemically synthesized E3 ligase ligand-linker conjugate. This compound incorporates a cereblon ligand based on Pomalidomide and a linker commonly employed in PROTAC technology.
Pack Size | Availability | Price/USD | Quantity |
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25 mg | 35 days | $ 523.00 |
Description | Pomalidomide-PEG3-C2-NH2 hydrochloride, also known as Cereblon Ligand-Linker Conjugate 5, is a chemically synthesized E3 ligase ligand-linker conjugate. This compound incorporates a cereblon ligand based on Pomalidomide and a linker commonly employed in PROTAC technology. |
In vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[2]. |
Synonyms | Pomalidomide-PEG3-C2-NH2 hydrochloride, Cereblon Ligand-Linker Conjugates 5 hydrochloride, E3ligaseLigand-LinkerConjugates30hydrochloride |
Molecular Weight | 484.93 |
Formula | C21H29ClN4O7 |
CAS No. | 2446474-09-3 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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Pomalidomide-PEG3-C2-NH2 hydrochloride 2446474-09-3 Pomalidomide-PEG3-C2-NH2 Hydrochloride Cereblon Ligand-Linker Conjugates 5 hydrochloride Cereblon Ligand-Linker Conjugates 5 Hydrochloride E3ligaseLigand-LinkerConjugates30hydrochloride Pomalidomide-PEG-3-C2-NH2 hydrochloride PomalidomidePEG3C2NH2 hydrochloride Pomalidomide PEG3 C2 NH2 hydrochloride inhibitor inhibit