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alpha-Cyperone

Name: alpha-Cyperone
Brand: TargetMol
SKU: T5S1981
Price: 50 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T5S1981Cas No. 473-08-5

Alias α-Cyperone, (+)-α-Cyperone

1. alpha-Cyperone (α-Cyperone) is a promising inhibitor of Hla production by S. aureus and protects lung cells from this bacterium. 2. alpha-Cyperone significantly inhibited PGE2 production by suppressing the LPS-induced expression of inducible COX-2 at both the mRNA and the protein levels , downregulated the production and mRNA expression of the inflammatory cytokine IL-6. 3. alpha-Cyperone inhibited actin cytoskeleton polymerization induced by APEC-O78 through down regulating the expression of Nck-2, Cdc42 and Rac1.

alpha-Cyperone

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Purity: 99.91%

Catalog No. T5S1981Alias α-Cyperone, (+)-α-CyperoneCas No. 473-08-5

Pack Size	Price	USA Warehouse	Global Warehouse
5 mg	$50	In Stock	In Stock
25 mg	$159	-	In Stock
50 mg	$239	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Questions

Batch Information

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Purity:99.91%

Appearance:Liquid

Color:Transparent

Resource Download

COA LCMS HNMR

Product Introduction

Bioactivity

Description

Synonyms

α-Cyperone, (+)-α-Cyperone

Chemical Properties

Molecular Weight	218.33
Formula	C₁₅H₂₂O
Cas No.	473-08-5
Smiles	CC(=C)[C@@H]1CC[C@@]2(C)CCC(=O)C(C)=C2C1
Relative Density.	0.97g/cm3

Storage & Solubility Information

Storage

store at low temperature,keep away from direct sunlight,The compound is unstable in solution. Please use soon | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 9 mg/mL (41.22 mM), Sonication is recommended. (The compound is unstable in solution, please use soon.)

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 1 mg/mL (4.58 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	4.5802 mL	22.9011 mL	45.8022 mL	229.0111 mL
5 mM	0.9160 mL	4.5802 mL	9.1604 mL	45.8022 mL
10 mM	0.4580 mL	2.2901 mL	4.5802 mL	22.9011 mL
20 mM	0.2290 mL	1.1451 mL	2.2901 mL	11.4506 mL

Calculator

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc