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Anti-Phospho-PRKG1 (Thr515) Polyclonal Antibody is a Rabbit antibody targeting Phospho-PRKG1 (Thr515). Anti-Phospho-PRKG1 (Thr515) Polyclonal Antibody can be used in WB.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
50 μL | $220 | 7-10 days | |
100 μL | $374 | 7-10 days | |
200 μL | $529 | 7-10 days |
Description | Anti-Phospho-PRKG1 (Thr515) Polyclonal Antibody is a Rabbit antibody targeting Phospho-PRKG1 (Thr515). Anti-Phospho-PRKG1 (Thr515) Polyclonal Antibody can be used in WB. |
Alias | PRKGR1B, PRKGR1A, PRKG1B, PRKG1 (p-Thr515), PRKG1 (p-T515), PRKG1, p-PRKG1 (Thr515), p-PRKG1 (T515), cGMP-Dependent Protein Kinase I, cGMP-Dependent Protein Kinase 1, cGKI, cGK1, cGK 1 |
Ig Type | IgG |
Reactivity | Human (predicted:Mouse,Rat) |
Verified Activity | Sample: JEG-3 (Human) Cell Lysate at 30 μg Primary: Anti-phospho-cGKI (Thr515) (TMAB-01486) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 74 kDa Observed band size: 74 kDa |
Application | WB |
Recommended Dose | WB: 1:500-2000 |
Antibody Type | Polyclonal |
Host Species | Rabbit |
Subcellular Localization | Cytoplasm. Colocalized with TRPC7 in the plasma membrane. |
Construction | Hybridoma Polyclonal Antibody |
Purification | Protein A purified |
Appearance | Liquid |
Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
Research Background | Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. PKG plays an important stimulatory role in platelet activation. |
Immunogen | KLH conjugated Synthesised phosphopeptide: human cGKI around the phosphorylation site of Thr515 |
Antigen Species | Human |
Gene ID | |
Uniprot ID | |
Biology Area | Platelets,Hypertrophy,Other Kinases |
Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
Transport | Shipping with blue ice. |
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