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Synonyms: HBPA1, GRS, BFL1, BCL2L5, BCL2 related protein A1, ACC-2, ACC2, ACC-1, ACC1
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 25 μL | $155 | 7-10 days | 7-10 days | |
| 50 μL | $272 | 7-10 days | 7-10 days | |
| 100 μL | $488 | 7-10 days | 7-10 days |
| Description | Anti-BCL2A1 Antibody (2U316) is a Rabbit antibody targeting BCL2A1. Anti-BCL2A1 Antibody (2U316) can be used in ICC/IF,IF,IHC-Fr,IHC-P,WB. |
| Synonyms | HBPA1, GRS, BFL1, BCL2L5, BCL2 related protein A1, ACC-2, ACC2, ACC-1, ACC1 |
| Ig Type | IgG |
| Clone | 2U316 |
| Reactivity | Human,Mouse (predicted:Rat) |
| Application | |
| Recommended Dose | WB: 1:500-2000; IHC-P: 1:50-200; IHC-Fr: 1:50-200; ICC/IF: 1:50-200; IF: 1:50-200 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cytoplasm. |
| Tissue Specificity | Seems to be restricted to the hematopoietic compartment. Expressed in peripheral blood, spleen, and bone marrow, at moderate levels in lung, small intestine and testis, at a minimal levels in other tissues. Also found in vascular smooth muscle cells and h |
| Construction | Recombinant Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | This gene encodes a member of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators that are involved in a wide variety of cellular activities such as embryonic development, homeostasis and tumorigenesis. The protein encoded by this gene is able to reduce the release of pro-apoptotic cytochrome c from mitochondria and block caspase activation. This gene is a direct transcription target of NF-kappa B in response to inflammatory mediators, and is up-regulated by different extracellular signals, such as granulocyte-macrophage colony-stimulating factor (GM-CSF), CD40, phorbol ester and inflammatory cytokine TNF and IL-1, which suggests a cytoprotective function that is essential for lymphocyte activation as well as cell survival. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
| Immunogen | A synthesized peptide: human Bcl 2 A1 |
| Antigen Species | Human |
| Gene Name | BCL2A1 |
| Gene ID | |
| Protein Name | Bcl-2-related protein A1 |
| Biology Area | Bcl2 Family |
| Function | Retards apoptosis induced by IL-3 deprivation. May function in the response of hemopoietic cells to external signals and in maintaining endothelial survival during infection. |
| Molecular Weight | Theoretical: 29 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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