Ga(III) protoporphyrin IX

Name: Ga(III) protoporphyrin IX
Brand: TargetMol
SKU: T39700
Rating: 4.5 (1 reviews)

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Catalog No. T39700Cas No. 222556-71-0

Ga(III)protoporphyrin-IX, a model for interporphyrin interactions in malaria pigment, possesses potent antibacterial effects against gram-negative, gram-positive, and acid-fast bacteria. It exhibits high solubility in methanol (MeOH) and serves as a malarial pigment analogue for drug development, as well as a potential antibacterial agent.

Ga(III) protoporphyrin IX

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Catalog No. T39700Cas No. 222556-71-0

Pack Size	Price	USA Warehouse	Global Warehouse	Quantity
25 mg	$1,520	Inquiry	Inquiry

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Product Introduction

Bioactivity

Description	Ga(III)protoporphyrin-IX, a model for interporphyrin interactions in malaria pigment, possesses potent antibacterial effects against gram-negative, gram-positive, and acid-fast bacteria. It exhibits high solubility in methanol (MeOH) and serves as a malarial pigment analogue for drug development, as well as a potential antibacterial agent.
In vitro	Ga(III)protoporphyrin-IX effectively binds to heme-containing proteins and enzymes in the cellular growth medium of the Gram-positive bacteria Enterococcus faecalis, which does not rely on heme for cell growth. This compound serves as a promising mimic of heme, offering potential for heme replacement/substitution applications[1].

Chemical Properties

Molecular Weight	629.36
Formula	C₃₄H₃₁GaN₄O₄
Cas No.	222556-71-0
Smiles	[H+].CC1=C(C=C)C2=CC3=[N]4C(=CC5=C(C)C(CCC([O-])=O)=C6C=C7C(CCC([O-])=O)=C(C)C8=[N]7[Ga+3]4([N-]2C1=C8)[N-]56)C(C=C)=C3C

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline /PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline /PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

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