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EMMPRIN/CD147 Protein, Human, Recombinant (His)

Catalog No. TMPJ-00160
Synonyms: 5F7, TCSF, OK Blood Group Antigen, Tumor Cell-Derived Collagenase Stimulatory Factor, Collagenase Stimulatory Factor, BSG, Leukocyte Activation Antigen M6, Basigin, Extracellular Matrix Metalloproteinase Inducer, EMMPRIN, CD147

Extracellular Matrix Metalloproteinase Inducer (EMMPRIN) belongs to the immunoglobulin superfamily, which has the homology to both the immunoglobulin V domain and MHC class II antigen β-chain. EMMPRIN is a transmembrane glycoprotein with different forms, resulting from different modes of glycosylation and N-terminal sequence variants. EMMPRIN can be expressed in breast cancer, oral squamous cell carcinoma, glioma, lymphoma, lung, bladder, and melanoma carcinomas cells. EMMPRIN promotes invasion, metastasis, growth, and survival of malignants cells, serves as a receptor for extracellular cyclophilinthe, may play a role in signal transduction.

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EMMPRIN/CD147 Protein, Human, Recombinant (His)
Pack Size Availability Price/USD Quantity
10 μg 5 days $ 97.00
50 μg 5 days $ 310.00
500 μg 5 days $ 1,900.00
1 mg 5 days $ 2,730.00
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Biological Description
Technical Params
Product Properties
Description Extracellular Matrix Metalloproteinase Inducer (EMMPRIN) belongs to the immunoglobulin superfamily, which has the homology to both the immunoglobulin V domain and MHC class II antigen β-chain. EMMPRIN is a transmembrane glycoprotein with different forms, resulting from different modes of glycosylation and N-terminal sequence variants. EMMPRIN can be expressed in breast cancer, oral squamous cell carcinoma, glioma, lymphoma, lung, bladder, and melanoma carcinomas cells. EMMPRIN promotes invasion, metastasis, growth, and survival of malignants cells, serves as a receptor for extracellular cyclophilinthe, may play a role in signal transduction.
Species Human
Expression System Human Cells
Tag C-6His
Accession Number P35613-2
Synonyms 5F7, TCSF, OK Blood Group Antigen, Tumor Cell-Derived Collagenase Stimulatory Factor, Collagenase Stimulatory Factor, BSG, Leukocyte Activation Antigen M6, Basigin, Extracellular Matrix Metalloproteinase Inducer, EMMPRIN, CD147
Amino Acid Ala22-His205
Construction Recombinant Human Extracellular Matrix Metalloproteinase Inducer is produced by our Mammalian expression system and the target gene encoding Ala22-His205 is expressed with a 6His tag at the C-terminus.
Protein Purity Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
Molecular Weight 30-40 KDa, reducing conditions
Endotoxin Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2.
Reconstitution Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. 
Stability & Storage

Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below.

Research Background Extracellular Matrix Metalloproteinase Inducer (EMMPRIN) belongs to the immunoglobulin superfamily, which has the homology to both the immunoglobulin V domain and MHC class II antigen β-chain. EMMPRIN is a transmembrane glycoprotein with different forms, resulting from different modes of glycosylation and N-terminal sequence variants. EMMPRIN can be expressed in breast cancer, oral squamous cell carcinoma, glioma, lymphoma, lung, bladder, and melanoma carcinomas cells. EMMPRIN promotes invasion, metastasis, growth, and survival of malignants cells, serves as a receptor for extracellular cyclophilinthe, may play a role in signal transduction.

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Keywords

EMMPRIN/CD147 Protein, Human, Recombinant (His) 5F7 TCSF OK Blood Group Antigen CD 147 Tumor Cell-Derived Collagenase Stimulatory Factor Collagenase Stimulatory Factor BSG Leukocyte Activation Antigen M6 Basigin Extracellular Matrix Metalloproteinase Inducer CD-147 EMMPRIN CD147 recombinant recombinant-proteins proteins protein

 

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