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Anti-PD-L1 Antibody-PE (2M478) (Synonyms: Pdl1, Pdcd1lg1, Pdcd1l1, CD274 molecule, B7h1, A530045L16Rik)
Catalog No. TMAY-00243P Copy Product Info
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Anti-PD-L1 Antibody-PE (2M478) is a PE-conjugated Rabbit antibody targeting PD-L1. Anti-PD-L1 Antibody-PE (2M478) can be used in FCM.
Anti-PD-L1 Antibody-PE (2M478)
Copy Product Info🥰Excellent
Catalog No. TMAY-00243P
Synonyms Pdl1, Pdcd1lg1, Pdcd1l1, CD274 molecule, B7h1, A530045L16Rik
Anti-PD-L1 Antibody-PE (2M478) is a PE-conjugated Rabbit antibody targeting PD-L1. Anti-PD-L1 Antibody-PE (2M478) can be used in FCM.
Anti-PD-L1 Antibody-PE
(2M478)
(2M478)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 25 T | $81 | 7-10 days | 7-10 days | |
| 100 T | $105 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
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Chemical Properties
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| Description | Anti-PD-L1 Antibody-PE (2M478) is a PE-conjugated Rabbit antibody targeting PD-L1. Anti-PD-L1 Antibody-PE (2M478) can be used in FCM. |
| Synonyms | Pdl1, Pdcd1lg1, Pdcd1l1, CD274 molecule, B7h1, A530045L16Rik |
| Ig Type | Rabbit IgG |
| Clone | 2M478 |
| Reactivity | Human |
| Specificity | Human PD-L1/B7-H1 |
| Verified Activity | Flow cytometric analysis of Human PDL1(CD274) expression on HCC827 cells.Cells were stained with PE-conjugated anti-Human-PDL1(CD274). The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells. |
| Application | |
| Recommended Dose | 10 μl/Test, 0.1 mg/ml |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human PD-L1/B7-H1/CD274 (rh PD-L1/B7-H1/CD274; TMPY-04343; NP_054862.1; Met1-Thr239) and conjugated with PE under optimum conditions, the unreacted PE was removed. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | PBS solution containing 0.5% BSA and 0.03%ProClin300 |
| Research Background | Programmed death-1 ligand-1 (PD-L1, CD274, B7-H1) has been identified as the ligand for the immunoinhibitory receptor programmed death-1(PD1/PDCD1) and has been demonstrated to play a role in the regulation of immune responses and peripheral tolerance. PD-L1/B7-H1 is a member of the growing B7 family of immune molecules and this protein contains one V-like and one C-like Ig domain within the extracellular domain, and together with PD-L2, are two ligands for PD1 which belongs to the CD28/CTLA4 family expressed on activated lymphoid cells. By binding to PD1 on activated T-cells and B-cells, PD-L1 may inhibit ongoing T-cell responses by inducing apoptosis and arresting cell-cycle progression. Accordingly, it leads to growth of immunogenic tumor growth by increasing apoptosis of antigen specific T cells and may contribute to immune evasion by cancers. PD-L1 thus is regarded as promising therapeutic target for human autoimmune disease and malignant cancers.Cancer ImmunotherapyCo-inhibitory Immune Checkpoint TargetsImmune CheckpointImmune Checkpoint Blockade: Blocking AntibodiImmune Checkpoint Blockade: PD-L1 / B7-H1 / CImmune Checkpoint Detection: AntibodiesImmune Checkpoint Detection: ELISA AntibodiesImmune Checkpoint Detection: FCM AntibodiesImmune Checkpoint Detection: ICC AntibodiesImmune Checkpoint Detection: IHC AntibodiesImmune Checkpoint Detection: WB AntibodiesImmune Checkpoint ProteinsImmune Checkpoint TargetsImmunotherapyPD-L1 / B7-H1 / CD274 Immune Checkpoint ProteTargeted Therapy |
| Conjucates | PE |
| Others Formats | Unconjugated/APC/FITC |
| Antibody Types Available | 4 |
| Immunogen | Recombinant Protein: Human PD-L1/B7-H1/CD274 Protein (TMPY-04343) |
| Antigen Species | Human |
| Biology Area | Cancer Drug Targets |
| Stability & Storage | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. |
| Transport | Shipping with blue ice. |
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