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GAS6 Protein, Human, Recombinant (aa 279-678, His) is expressed in HEK293 Cells. The accession number is Q14393-2.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 μg | $687 | 7-10 days | |
1 mg | $4,560 | 7-10 days |
Biological Activity | Immobilized Human GAS6, His Tag at 5 μg/ml (100 μl/well) on the plate. Dose response curve for Human Axl, hFc Tag with the EC50 of 2.6 ng/ml determined by ELISA.Human GAS6, His Tag immobilized on CM5 Chip can bind Human TYRO3, His Tag with an affinity constant of 2.36 μM as determined in SPR assay (Biacore T200). |
Description | GAS6 Protein, Human, Recombinant (aa 279-678, His) is expressed in HEK293 Cells. The accession number is Q14393-2. |
Species | Human |
Expression System | HEK293 Cells |
Tag | C-His |
Accession Number | Q14393-2 |
Synonyms | FLJ34709,DKFZp666G247,AXSF,AXLLG |
Construction | Ala49-Ala678 |
Protein Purity | > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC |
Molecular Weight | 70.60 kDa (Predicted); 71-75 kDa (Due to glycosylation) |
Endotoxin | Less than 1EU per μg by the LAL method. |
Formulation | Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
Stability & Storage | Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. After reconstitution under sterile conditions, samples are stable for up to three months at -20℃ to -80℃. |
Shipping | In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice. |
Research Background | Growth arrest-specific 6, also known as Gas6, is a human gene encoding the Gas6 protein, which was originally found to be upregulated in growth-arrested fibroblasts. Gas6 is a member of the vitamin K-dependent family of proteins expressed in many human tissues and regulates several biological processes in cells, including proliferation, survival and migration, by binding to its receptors Tyro3, Axl and Mer (TAM). |
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