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Anti-NOD2 Polyclonal Antibody is a Rabbit antibody targeting NOD2. Anti-NOD2 Polyclonal Antibody can be used in WB.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
50 μL | $220 | 7-10 days | |
100 μL | $373 | 7-10 days | |
200 μL | $529 | 7-10 days |
Description | Anti-NOD2 Polyclonal Antibody is a Rabbit antibody targeting NOD2. Anti-NOD2 Polyclonal Antibody can be used in WB. |
Alias | Nucleotide-binding oligomerization domain-containing protein 2, NOD2, Caspase recruitment domain-containing protein 15, CARD15 |
Ig Type | IgG |
Reactivity | Human (predicted:Mouse,Rat,Dog,Pig,Cow,Horse,Rabbit) |
Verified Activity | 1. Sample: MCF-7 (Human) Cell Lysate at 30 μg Primary: Anti-NOD2 (TMAB-01251) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 114 kDa Observed band size: 114 kDa 2. Sample: A549 (Human) Cell Lysate at 30 μg MCF-7 (Human) Cell Lysate at 30 μg Primary: Anti-NOD2 (TMAB-01251) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 114 kDa Observed band size: 114 kDa |
Application | WB |
Recommended Dose | WB: 1:500-2000 |
Antibody Type | Polyclonal |
Host Species | Rabbit |
Subcellular Localization | Cytoplasm. |
Construction | Hybridoma Polyclonal Antibody |
Purification | Protein A purified |
Appearance | Liquid |
Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
Research Background | Defects in NOD2 are the cause of sarcoidosis early-onset (EOS) . EOS is a form of sarcoidosis manifesting in children younger than 4 years of age. Sarcoidosis is an idiopathic, systemic, inflammatory disease characterized by the formation of immune granulomas in involved organs. Granulomas predominantly invade the lungs and the lymphatic system, but also skin, liver, spleen, eyes and other organs may be involved. Early-onset sarcoidosis is quite rare and has a distinct triad of skin, joint and eye disorders, without apparent pulmonary involvement. Compared with an asymptomatic and sometimes naturally disappearing course of the disease in older children, early-onset sarcoidosis is progressive and in many cases causes severe complications, such as blindness, joint destruction and visceral involvement. |
Immunogen | KLH conjugated synthetic peptide: human CARD15 |
Antigen Species | Human |
Gene ID | |
Uniprot ID | |
Biology Area | CARD Family |
Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
Transport | Shipping with blue ice. |
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