Plecanatide acetate

Name: Plecanatide acetate
Brand: TargetMol
SKU: T12501
Rating: 4.5 (1 reviews)

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Catalog No. T12501Cas No. 1075732-84-1

Plecanatide acetate is a agonist of guanylate cyclase-C (GC-C) receptor( EC50 of 190 nM in T84 cells), and shows anti-inflammatory activity in models of murine colitis.

Plecanatide acetate

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Catalog No. T12501Cas No. 1075732-84-1

Plecanatide acetate is a agonist of guanylate cyclase-C (GC-C) receptor( EC50 of 190 nM in T84 cells), and shows anti-inflammatory activity in models of murine colitis.

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$223	35 days	35 days
5 mg	$867	35 days	35 days
10 mg	$1,390	35 days	35 days
25 mg	$2,870	35 days	35 days

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

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Product Introduction

Bioactivity

Description	Plecanatide acetate is a agonist of guanylate cyclase-C (GC-C) receptor( EC50 of 190 nM in T84 cells), and shows anti-inflammatory activity in models of murine colitis.
Targets&IC50	GC-C (T84 cells):190 nM (EC50)
In vitro	Plecanatide acetate is a GC-C receptor agonist, binds and activates GC-C receptor(EC50 of 190 nM in T84 cells)[1].

Chemical Properties

Molecular Weight	1741.94
Formula	C₆₇H₁₀₈N₁₈O₂₈S₄
Cas No.	1075732-84-1
Relative Density.	no data available
Sequence	Asn-Asp-Glu-Cys-Glu-Leu-Cys-Val-Asn-Val-Ala-Cys-Thr-Gly-Cys-Leu (Disulfide bridge: Cys4-Cys12; Cys7-Cys15)
Sequence Short	NDECELCVNVACTGCL (Disulfide bridge: Cys4-Cys12; Cys7-Cys15)

Storage & Solubility Information

Storage

keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

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Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

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mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

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