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Anti-CD28 Antibody-PerCP (1N81) is a PerCP-conjugated Rabbit antibody targeting CD28. Anti-CD28 Antibody-PerCP (1N81) can be used in FCM.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
25 T | $104 | 7-10 days | |
100 T | $327 | 7-10 days |
Description | Antibody Type: Rabbit Monoclonal Application: FCM Reactivity: Human |
Alias | CD28 molecule |
Ig Type | Rabbit IgG |
Clone | 1N81 |
Reactivity | Human |
Verified Activity | Flow cytometric analysis of Human CD28 expression on human whole blood lymphocytes. Cells were stained with PerCP-conjugated anti-Human CD28. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells. |
Application | FCM |
Recommended Dose | 10 μl/Test, 0.1 mg/ml |
Antibody Type | Monoclonal |
Host Species | Rabbit |
Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human CD28/TP44 (rh CD28/TP44; P10747-1Met1-Pro152) and conjugated with PerCP under optimum conditions, the unreacted PerCP was removed. |
Purification | Protein A |
Appearance | Liquid |
Formulation | PBS solution containing 0.5% BSA and 0.03%ProClin300 |
Research Background | CD28 (Cluster of Differentiation 28) is a disulphide-bonded glycoprotein belonging to the immunoglobulin (Ig) superfamily, and structurally consists of a single Ig V-like extracellular domain, a transmembrane domain and an intracellular domain. Mouse CD28 is constitutively expressed on the surface of all murine T cells and on developing thymocytes as disulfide-linked homodimers or as monomers. CD28 can binds the B7-1 and B7-2 ligand, and together perform important functions in the T and B cell response pathways. B7/CD28 family members, which can augment or antagonize T-cell receptor signaling, in the regulation of central and peripheral T-cell tolerance. CD28 is thus involved in T-cell activation, the induction of cell proliferation and cytokine production and promotion of T-cell survival.Cancer ImmunotherapyCo-stimulatory Immune Checkpoint TargetsImmune CheckpointImmune Checkpoint Detection: AntibodiesImmune Checkpoint Detection: ELISA AntibodiesImmune Checkpoint Detection: FCM AntibodiesImmune Checkpoint Detection: IHC AntibodiesImmune Checkpoint Detection: WB AntibodiesImmune Checkpoint TargetsImmunotherapyTargeted Therapy |
Conjucates | PerCP |
Others Formats | Unconjugated/FITC |
Antibody Types Available | 3 |
Immunogen | Recombinant Protein: Human CD28/TP44 Protein |
Antigen Species | Human |
Biology Area | ITIM/ITAM Immunoreceptors and Related Molecules, Cancer Drug Targets |
Stability & Storage | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. |
Transport | Shipping with blue ice. |
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