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IL-28B Protein, Human, Recombinant

Catalog No. TMPJ-00076
Synonyms: IL-28C, IFN-λ-4, IFNL4, Interferon λ-4, IL28B, IL-28B, Interleukin-28C, ZCYTO22, IFN-Lambda-3, Cytokine Zcyto22, Interferon Lambda-4, Interleukin-28B, Interferon λ-3, IFNL3, IFN-Lambda-4, IL28C, Interferon Lambda-3, IFN-λ-3

Interleukin-28B, also known as Cytokine Zcyto22, Interferon lambda-3, Interferon lambda-4, IFNL3, IFNL4, ZCYTO22 and IL28B, is a secreted cytokine which belongs to the IL-28/IL-29 family. IL-28 has also been shown to play a role in the adaptive immune response. IL28B has immunomodulatory activity and up-regulates MHC class I antigen expression. IL28B displays potent antiviral activity and antitumor activity. In addition, IL28B is a ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IL28RA. The ligand/receptor complex seems to signal through the Jak-STAT pathway.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.
IL-28B Protein, Human, Recombinant
Pack Size Availability Price/USD Quantity
10 μg 5 days $ 129.00
50 μg 5 days $ 390.00
500 μg 5 days $ 1,900.00
1 mg 5 days $ 2,730.00
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Biological Description
Technical Params
Product Properties
Description Interleukin-28B, also known as Cytokine Zcyto22, Interferon lambda-3, Interferon lambda-4, IFNL3, IFNL4, ZCYTO22 and IL28B, is a secreted cytokine which belongs to the IL-28/IL-29 family. IL-28 has also been shown to play a role in the adaptive immune response. IL28B has immunomodulatory activity and up-regulates MHC class I antigen expression. IL28B displays potent antiviral activity and antitumor activity. In addition, IL28B is a ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IL28RA. The ligand/receptor complex seems to signal through the Jak-STAT pathway.
Species Human
Expression System Human Cells
Tag None
Accession Number Q8IZI9
Synonyms IL-28C, IFN-λ-4, IFNL4, Interferon λ-4, IL28B, IL-28B, Interleukin-28C, ZCYTO22, IFN-Lambda-3, Cytokine Zcyto22, Interferon Lambda-4, Interleukin-28B, Interferon λ-3, IFNL3, IFN-Lambda-4, IL28C, Interferon Lambda-3, IFN-λ-3
Amino Acid Val22-Val196
Construction Recombinant Human Interleukin-28B is produced by our Mammalian expression system and the target gene encoding Val22-Val196 is expressed.
Protein Purity Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
Molecular Weight 18 KDa, reducing conditions
Endotoxin Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, 1mM EDTA, pH 7.4.
Reconstitution Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. 
Stability & Storage

Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below.

Research Background Interleukin-28B, also known as Cytokine Zcyto22, Interferon lambda-3, Interferon lambda-4, IFNL3, IFNL4, ZCYTO22 and IL28B, is a secreted cytokine which belongs to the IL-28/IL-29 family. IL-28 has also been shown to play a role in the adaptive immune response. IL28B has immunomodulatory activity and up-regulates MHC class I antigen expression. IL28B displays potent antiviral activity and antitumor activity. In addition, IL28B is a ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IL28RA. The ligand/receptor complex seems to signal through the Jak-STAT pathway.

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Keywords

IL-28B Protein, Human, Recombinant IL-28C IFN-λ-4 IFNL4 ZCYTO 22 Interferon λ-4 IL28B IFNL-3 IFNL 4 IL-28B Interleukin-28C ZCYTO22 IFN-Lambda-3 Cytokine Zcyto22 Interferon Lambda-4 Interleukin-28B IFNL-4 Interferon λ-3 IFNL3 IFN-Lambda-4 IL28C Interferon Lambda-3 IFNL 3 IFN-λ-3 ZCYTO-22 recombinant recombinant-proteins proteins protein

 

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