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m-PEG24-NHS ester is a PEG-based PROTAC linker commonly used in the synthesis of PROTAC.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
5 mg | $42 | In Stock | |
10 mg | $59 | In Stock | |
25 mg | $98 | In Stock | |
50 mg | $137 | In Stock | |
100 mg | $188 | In Stock |
Description | m-PEG24-NHS ester is a PEG-based PROTAC linker commonly used in the synthesis of PROTAC. |
In vitro | The NHS ester group of m-PEG24-NHS ester can react with primary amines on proteins, peptides, or oligonucleotides to form stable amide bonds, enabling PEGylation of the molecule and thereby increasing its water solubility and stability. Commonly used in the synthesis of antibody–drug conjugates (ADCs), protein modification, oligonucleotide modification, and PROTACs, where it serves as a linker to enhance the pharmacokinetic properties of the molecule. [1] |
Molecular Weight | 1214.39 |
Formula | C54H103NO28 |
Cas No. | 2395839-96-8 |
Smiles | O=C(ON1C(=O)CCC1=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOC |
Relative Density. | 1.18 g/cm3 (Predicted) |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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