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PF-06815189

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Catalog No. T24624

PF-06815189 is a phosphodiesterase 2A inhibitor. PF-06815189 also has good selectivity over other phosphodiesterases with a 1000-fold margin (PDE5/2 selectivity: 2439 nM/0.4 nM).

PF-06815189

PF-06815189

😃Good
Catalog No. T24624
PF-06815189 is a phosphodiesterase 2A inhibitor. PF-06815189 also has good selectivity over other phosphodiesterases with a 1000-fold margin (PDE5/2 selectivity: 2439 nM/0.4 nM).
Pack SizePriceAvailabilityQuantity
25 mg$2,420 3-6 months
50 mg$3,180 3-6 months
100 mg$4,300 3-6 months
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Product Introduction

Bioactivity
Description
PF-06815189 is a phosphodiesterase 2A inhibitor. PF-06815189 also has good selectivity over other phosphodiesterases with a 1000-fold margin (PDE5/2 selectivity: 2439 nM/0.4 nM).
Targets&IC50
PDE2A:0.4 nM
Chemical Properties
Molecular Weight418.38
FormulaC19H17F3N6O2
Relative Density.no data available
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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2 Enter the in vivo formulation:
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

PF06815189PF 06815189PF-06815189
Related Tags: buy PF-06815189 | purchase PF-06815189 | PF-06815189 cost | order PF-06815189 | PF-06815189 chemical structure | PF-06815189 formula | PF-06815189 molecular weight
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