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Anti-CD2 Antibody-PE (5C597)
🥰Excellent
Catalog No. TMAY-01422P
Anti-CD2 Antibody-PE (5C597) is a PE-conjugated Rabbit antibody targeting CD2. Anti-CD2 Antibody-PE (5C597) can be used in FCM.
Anti-CD2 Antibody-PE (5C597)
Anti-CD2 Antibody-PE (5C597)
🥰Excellent
Catalog No. TMAY-01422P
Anti-CD2 Antibody-PE (5C597) is a PE-conjugated Rabbit antibody targeting CD2. Anti-CD2 Antibody-PE (5C597) can be used in FCM.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-CD2 Antibody-PE (5C597) is a PE-conjugated Rabbit antibody targeting CD2. Anti-CD2 Antibody-PE (5C597) can be used in FCM. |
| Ig Type | Monoclonal Rabbit IgG |
| Clone | 5C597 |
| Reactivity | Human |
| Verified Activity | Flow cytometric analysis of Human CD2 expression on human whole blood lymphocytes. Cells were stained with PE-conjugated anti-Human CD2. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of viable lymphocytes. |
| Application | FCM |
| Recommended Dose | 10 μl/Test, 0.1 mg/ml |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human CD2 (rh CD2; TMPY-01255; NP_001758.2; Met1-Asp209) and conjugated with PE under optimum conditions, the unreacted PE was removed. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | PBS solution containing 0.5% BSA and 0.09% sodium azide |
| Research Background | T-cell surface antigen CD2, also known as T-cell surface antigen T11/Leu-5, and SRBC, is a single-pass type I membrane protein. It contains one Ig-like C2-type domain and one Ig-like V-type domain. CD2 is a cell adhesion molecule expressed on T cells and is recognized as a target for CD48 (rats) and CD58 (humans). CD2 has been shown to set quantitative thresholds in T cell activation both in vivo and in vitro. Further, intracellular CD2 signaling pathways and networks are being discovered by the identification of several cytosolic tail binding proteins. CD2 interacts with lymphocyte function-associated antigen (LFA-3) and CD48/BCM1 to mediate adhesion between T-cells and other cell types. CD2 is implicated in the triggering of T-cells, the cytoplasmic domain of CD2 is implicated in the signaling function. The complex of CD2 and CD58 also plays an important role in enhancing the adhesion of T lymphocytes to target cells, and promoting hyperplasia and activation of T lymphocytes. As a cell surface glycoprotein, CD2 expressed on most human T cells and natural killer (NK) cells and plays an important role in mediating cell adhesion in both T-lymphocytes and in signal transduction.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy |
| Conjucates | PE |
| Others Formats | Unconjugated/APC/PerCP/FITC |
| Antibody Types Available | 5 |
| Immunogen | Recombinant Human CD2 Protein (TMPY-01255) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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