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Anti-OX40/TNFRSF4 Antibody-PE (2E203)
🥰Excellent
Catalog No. TMAY-00885P
Anti-OX40/TNFRSF4 Antibody-PE (2E203) is a PE-conjugated Mouse antibody targeting OX40/TNFRSF4. Anti-OX40/TNFRSF4 Antibody-PE (2E203) can be used in FCM.
Anti-OX40/TNFRSF4 Antibody-PE (2E203)
Anti-OX40/TNFRSF4 Antibody-PE (2E203)
🥰Excellent
Catalog No. TMAY-00885P
Anti-OX40/TNFRSF4 Antibody-PE (2E203) is a PE-conjugated Mouse antibody targeting OX40/TNFRSF4. Anti-OX40/TNFRSF4 Antibody-PE (2E203) can be used in FCM.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-OX40/TNFRSF4 Antibody-PE (2E203) is a PE-conjugated Mouse antibody targeting OX40/TNFRSF4. Anti-OX40/TNFRSF4 Antibody-PE (2E203) can be used in FCM. |
| Ig Type | Monoclonal Mouse IgG1 |
| Clone | 2E203 |
| Reactivity | Human |
| Verified Activity | Flow cytometric analysis of Human OX40 expression on PHA-activated human whole blood lymphocytes. Cells were stained with PE-conjugated anti-Human OX40. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of viable lymphocytes. |
| Application | FCM |
| Recommended Dose | 10 μL/Test, 0.1 mg/mL |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This product is a recombinant monoclonal antibody expressed from HEK293 cells, and conjugated with PE under optimum conditions, the unreacted PE was removed. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | PBS solution containing 0.5% BSA and 0.03%ProClin300 |
| Research Background | OX40 (CD134) and its binding partner, OX40L (CD252), are members of the tumor necrosis factor receptor/tumor necrosis factor superfamily, is known to break an existing state of tolerance in malignancies, leading to a reactivation of antitumor immunity. The interaction between OX40 and OX40L plays an important role in antigen-specific T-cell expansion and survival. OX40 and OX40L also regulate cytokine production from T cells, antigen-presenting cells, natural killer cells, and natural killer T cells, and modulate cytokine receptor signaling. In line with these important modulatory functions, OX40-OX40L interactions have been found to play a central role in the development of multiple inflammatory and autoimmune diseases, making them attractive candidates for intervention in the clinic. Conversely, stimulating OX40 has shown it to be a candidate for therapeutic immunization strategies for cancer and infectious disease.Cancer ImmunotherapyCo-stimulatory Immune Checkpoint TargetsImmune CheckpointImmune Checkpoint Detection: AntibodiesImmune Checkpoint Detection: ELISA AntibodiesImmune Checkpoint Detection: WB AntibodiesImmune Checkpoint ProteinsImmune Checkpoint TargetsImmunotherapyTargeted Therapy |
| Conjucates | PE |
| Others Formats | Unconjugated/FITC |
| Antibody Types Available | 3 |
| Immunogen | Recombinant Human OX40 Protein (TMPY-01423) |
| Antigen Species | Human |
| Biology Area | Cancer Drug Targets |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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