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Anti-SRPK1 Antibody (4K294)
😃Good
Catalog No. TMAY-02297
Alias SRSF protein kinase 1, SFRSK1, RP3-422H11.1
Anti-SRPK1 Antibody (4K294) is a Mouse antibody targeting SRPK1. Anti-SRPK1 Antibody (4K294) can be used in ELISA.
Anti-SRPK1 Antibody (4K294)
Anti-SRPK1 Antibody (4K294)
😃Good
Catalog No. TMAY-02297Alias SRSF protein kinase 1, SFRSK1, RP3-422H11.1
Anti-SRPK1 Antibody (4K294) is a Mouse antibody targeting SRPK1. Anti-SRPK1 Antibody (4K294) can be used in ELISA.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $199 | 7-10 days |
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Product Introduction
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Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-SRPK1 Antibody (4K294) is a Mouse antibody targeting SRPK1. Anti-SRPK1 Antibody (4K294) can be used in ELISA. |
| Alias | SRSF protein kinase 1, SFRSK1, RP3-422H11.1 |
| Ig Type | Monoclonal Mouse IgG2a |
| Clone | 4K294 |
| Reactivity | Human |
| Application | ELISA |
| Recommended Dose | ELISA: 1:1000-1:2000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human SRPK1 (rh SRPK1; TMPY-04567; AAH38292.1; Glu2-Ser655). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Serine / threonine-protein kinase SRPK1, also known as SFRS protein kinase 1, Serine/arginine-rich protein-specific kinase 1, SR-protein-specific kinase 1 and SRPK1, is a cytoplasm and nucleus protein that belongs to the protein kinase superfamily and CMGC Ser/Thr protein kinase family. Isoform 2 of SRPK1 is predominantly expressed in the testis but is also present at lower levels in heart, ovary, small intestine, liver, kidney, pancreas and skeletal muscle. Isoform 1 of SRPK1 is only seen in the testis, at lower levels than isoform 2. SRPK1 hyperphosphorylates RS domain-containing proteins such as SFRS1, SFRS2 and ZRSR2 on serine residues during metaphase but at lower levels during interphase. SRPK1 plays a central role in the regulatory network for splicing, controlling the intranuclear distribution of splicing factors in interphase cells and the reorganization of nuclear speckles during mitosis. SRPK1 locks onto SFRS1 to form a stable complex and processively phosphorylates the RS domain. SRPK1 appears to mediate HBV core protein phosphorylation which is a prerequisite for pregenomic RNA encapsidation into viral capsids. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Human SRPK1 Protein (TMPY-04567) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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